Evidence map›Paper›PMID 33716793›Full record

SynthesisFrontiers in physiology2021

Cerebrovascular Reactivity Measurement Using Magnetic Resonance Imaging: A Systematic Review.

Emilie Sleight, Michael S Stringer, Ian Marshall, Joanna M Wardlaw, Michael J Thrippleton

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cerebrovascular reactivity delay measured by blood oxygen level dependent magnetic resonance imaging and gas challenges: A systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Emilie SleightCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Michael S StringerCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Ian MarshallCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Joanna M WardlawCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Michael J ThrippletonCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Funding

Chief Scientist Office ETM/326
6 · The paper itself

Abstract

Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the health of the vasculature and is therefore a key parameter for studying cerebrovascular diseases such as stroke, small vessel disease and dementias. MRI allows

Indexed as

arterial spin labelling MRIblood oxygen-level dependentcerebrovascular reactivityHypercapnia (CO(2)) inhalationmagnetic resonance imagingsystematic review

Identifiers

PMID33716793
PMCPMC7947694

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.