Evidence map›Paper›PMID 33716760›Full record

ArticleFrontiers in physiology2021

Baseline Arterial CO

Raphael R Perim, Mohamed El-Chami, Elisa J Gonzalez-Rothi, Gordon S Mitchell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Phrenic long-term facilitation following acute intermittent hypercapnic-hypoxia in rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raphael R PerimDepartment of Physical Therapy, McKnight Brain Institute, Center for Respiratory Research and Rehabilitation, University of Florida, Gainesville, FL, United States.
Mohamed El-ChamiDepartment of Physical Therapy, McKnight Brain Institute, Center for Respiratory Research and Rehabilitation, University of Florida, Gainesville, FL, United States.
Elisa J Gonzalez-RothiDepartment of Physical Therapy, McKnight Brain Institute, Center for Respiratory Research and Rehabilitation, University of Florida, Gainesville, FL, United States.
Gordon S MitchellDepartment of Physical Therapy, McKnight Brain Institute, Center for Respiratory Research and Rehabilitation, University of Florida, Gainesville, FL, United States.
University of Florida · US

Funding

Regulation of Intermittent Hypoxia-Induced Respiratory Motor PlasticityR01HL148030 · NHLBI · UNIVERSITY OF FLORIDA · PI MITCHELL, GORDON S. · 2019 to 2022
$2.4M
NHLBI NIH HHS R01 HL148030
6 · The paper itself

Abstract

Moderate acute intermittent hypoxia (mAIH) elicits a progressive increase in phrenic motor output lasting hours post-mAIH, a form of respiratory motor plasticity known as phrenic long-term facilitation (pLTF). mAIH-induced pLTF is initiated by activation of spinally-projecting raphe serotonergic neurons during hypoxia and subsequent serotonin release near phrenic motor neurons. Since raphe serotonergic neurons are also sensitive to pH and CO

Indexed as

acute intermittent hypoxiaPaCO2phrenic activityphrenic long-term facilitationrespiratory plasticity

Identifiers

PMID33716760
PMCPMC7943620
OpenAlexW3131013818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.