Evidence map›Paper›PMID 33716598›Full record

ArticleInternational journal of peptide research and therapeutics2021

Bioprocess Optimization of Nutritional Parameters for Enhanced Anti-leukemic L-Asparaginase Production by

Maurice Ekpenyong, Atim Asitok, Richard Antigha, Nkpa Ogarekpe, Ubong Ekong, Marcus Asuquo, Joseph Essien, Sylvester Antai

Open access · bronzeAbstract read
In one paragraph

Article in International journal of peptide research and therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maurice EkpenyongEnvironmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar, Calabar, Nigeria.ORCID https://orcid.org/0000-0001-9601-5546
Atim AsitokEnvironmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar, Calabar, Nigeria.ORCID https://orcid.org/0000-0002-6752-7048
Richard AntighaDepartment of Civil Engineering, Cross River University of Technology, Calabar, Cross River State Nigeria.ORCID https://orcid.org/0000-0002-2027-9825
Nkpa OgarekpeDepartment of Civil Engineering, Cross River University of Technology, Calabar, Cross River State Nigeria.ORCID https://orcid.org/0000-0001-5436-9434
Ubong EkongDepartment of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmacy, University of Calabar, Calabar, Nigeria.
Marcus AsuquoDepartment of Hematology, University of Calabar Teaching Hospital, Calabar, Nigeria.
Joseph EssienDepartment of Microbiology, Faculty of Science, University of Uyo, Uyo, Nigeria.ORCID https://orcid.org/0000-0002-7844-9954
Sylvester AntaiEnvironmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar, Calabar, Nigeria.ORCID https://orcid.org/0000-0002-2196-471X
University of Calabar · NGUniversity of Cross River State · NGUniversity of Uyo · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequential optimization of bioprocess nutritional conditions for production of glutaminase-near-free L-asparaginase by

Indexed as

Anti-cancer activityAspergillus candidusL-Asparaginase activityRenewable substratesSelectivity indexSequential optimization

Identifiers

PMID33716598
PMCPMC7942987
OpenAlexW3125920147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.