ArticleReactive & functional polymers2021
Molecularly Imprinted Micelles for Fluorescent Sensing of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).
Article in Reactive & functional polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Controlling Photocatalytic Hydrodechlorination of Aryl Chlorides via Supramolecular Organization on a Molecularly Imprinted Nanoparticle.Organic letters · 2026Article
- Direct synthesis of molecularly imprinted nanozymes with a biomimetic catalytic motif for glycosidic bond cleavage.Frontiers in chemistry · 2026Article
- Development of a "turn off" fluorescent molecularly imprinted nanoparticle-based sensor for selective captopril quantification in synthetic urine and wastewater samples.Mikrochimica acta · 2024Article
- Acid-Functionalized Artificial Enzymes with Tunable Selectivity for Vinyl Ether Hydrolysis.The Journal of organic chemistry · 2023Article
- Polymeric Micellar Systems-A Special Emphasis on "Smart" Drug Delivery.Pharmaceutics · 2023Review
- The Evolution of Molecular Recognition: From Antibodies to Molecularly Imprinted Polymers (MIPs) as Artificial Counterpart.Journal of functional biomaterials · 2022Review
- Substrate Protection in Controlled Enzymatic Transformation of Peptides and Proteins.Chembiochem : a European journal of chemical biology · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used over-the-counter drugs and their uncontrolled disposal is a significant environmental concern. Although their fluorescent sensing is a desirable method of detection for its sensitivity and simplicity, the structural similarity of the drugs makes the design of selective sensors highly challenging. A thiourea-based fluorescent functional monomer was identified in this work to enable highly efficient synthesis of molecularly imprinted nanoparticle (MINP) sensors for NSAIDs such as Indomethacin or Tolmetin. Micromolar binding affinities were obtained in aqueous solution, with binding selectivities comparable to those reported for polyclonal antibodies. The detection limit was ~50 ng/mL in aqueous solution, and common carboxylic acids such as acetic acid, benzoic acid, and citric acid showed negligible interference.
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Registered trials
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