Evidence map›Paper›PMID 33716516›Full record

ReviewClinical medicine insights. Blood disorders2021

Management of Primary Plasma Cell Leukemia Remains Challenging Even in the Era of Novel Agents.

Chakra P Chaulagain, Maria-Julia Diacovo, Amy Van, Felipe Martinez, Chieh-Lin Fu, Antonio Martin Jimenez Jimenez, Wesam Ahmed, Faiz Anwer

Open access · diamondAbstract readReview
In one paragraph

Review in Clinical medicine insights. Blood disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chakra P ChaulagainDepartment of Hematology and Oncology, Maroone Cancer Center, Myeloma and Amyloidosis Program, Cleveland Clinic Florida, Weston, FL, USA.ORCID https://orcid.org/0000-0002-4641-2217
Maria-Julia DiacovoDepartment of Pathology, Cleveland Clinic Florida, Weston, FL, USA.
Amy VanDepartment of Internal Medicine, Cleveland Clinic Florida, Weston FL, USA.
Felipe MartinezDepartment of Radiology, Cleveland Clinic Florida, Weston, FL, USA.
Chieh-Lin FuDepartment of Hematology and Oncology, Maroone Cancer Center, Myeloma and Amyloidosis Program, Cleveland Clinic Florida, Weston, FL, USA.
Antonio Martin Jimenez JimenezDivision of Stem Cell Transplant & Cell Therapy, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL, USA.
Wesam AhmedDepartment of Hematology and Oncology, Maroone Cancer Center, Myeloma and Amyloidosis Program, Cleveland Clinic Florida, Weston, FL, USA.
Faiz AnwerMultiple Myeloma Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0001-6914-7439
Cleveland Clinic Florida · USCleveland Clinic · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary plasma cell leukemia (PCL) is a rare and aggressive variant of multiple myeloma (MM). PCL is characterized by peripheral blood involvement by malignant plasma cells and an aggressive clinical course leading to poor survival. There is considerable overlap between MM and PCL with respect to clinical, immunophenotypic, and cytogenetic features, but circulating plasma cell count exceeding 20% of peripheral blood leukocytes or an absolute plasma cell count of >2000/mm

Indexed as

autologous hematopoietic stem cell transplantationmultiple myelomanovel agentsPlasma cell leukemia

Identifiers

PMID33716516
PMCPMC7917418
OpenAlexW3134555729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.