Trial reportWorld journal of gastroenterology2021
Endoscopic full-thickness resection using an over-the-scope device: A prospective study.
Trial report in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Endoscopic full-thickness resection of upper gastrointestinal tract: a review on closure techniques.Clinical endoscopy · 2026Review
- Endoscopic full-thickness resection for the treatment of gastric gastrointestinal stromal tumors.Clinical endoscopy · 2026Review
- Endoscopic full-thickness resection for early gastric cancer: a multicenter retrospective study from the National Early Gastrointestinal Cancer Cohort (NEGCC).International journal of surgery (London, England) · 2026Article
- Efficacy and safety of ESR-EB and ESE in the treatment of small gastric muscularis propria tumours: single-centre prospective cohort study.Scientific reports · 2025Article
- Risk factors with nomogram construction for moderate to severe pain after endoscopic full-thickness resection.World journal of gastroenterology · 2025Article
- Advancements in endoscopic resection of gastrointestinal stromal tumors: Techniques, outcomes, and perspectives.World journal of gastrointestinal surgery · 2025Review
- Advances in endoscopic closure techniques for endoscopic full-thickness resection.World journal of gastrointestinal endoscopy · 2025Review
- Comparison of endoscopic resection, laparoscopic resection, and laparoscopic endoscopic cooperative surgery in esophageal or gastric subepithelial lesions in a Thai medical school.Asian biomedicine : research, reviews and news · 2025Article
- Endoscopic full-thickness resectionWorld journal of gastrointestinal surgery · 2025Article
- Endoscopic resection of gastric gastrointestinal stromal tumor using clip-and-cut endoscopic full-thickness resection: a single-center, retrospective cohort in Korea.Clinical endoscopy · 2024Article
- The Role of Specialized Instruments for Advanced Endoscopic Resections in Gastrointestinal Disease.Life (Basel, Switzerland) · 2023Article
- Non-exposed endoscopic wall-inversion surgery with one-step nucleic acid amplification for early gastrointestinal tumors: Personal experience and literature review.World journal of gastroenterology · 2023Review
- Band-assisted endoscopic mucosal resection for small (≤ 1.5 cm) submucosal tumors originating from the muscularis propria in the gastric fundus: a prospective study.Surgical endoscopy · 2023Article
- Feasibility and efficacy of endoscopic purse-string suture-assisted closure for mucosal defects induced by endoscopic manipulations.World journal of gastroenterology · 2023Observational
- Advances of endoscopic and surgical management in gastrointestinal stromal tumors.Frontiers in surgery · 2023Review
- Resection of subepithelial lesions by a novel technique: "Band endoscopic full-thickness resection".Endoscopy · 2022Article
- A Study of a Novel Disposable Endoscopic Purse-String Suture Auxiliary Instrument for the Treatment of Full-Thickness Gastric Wall Defects.Journal of digestive diseasesArticle
- Gastrointestinal endoscopy and visceral surgery: current status and potentials for interdisciplinary patient care.Therapeutic advances in gastrointestinal endoscopyReview
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic submucosal dissection to treat mucosal and submucosal lesions sometimes results in low rates of microscopically margin-negative (R0) resection. Endoscopic full-thickness resection (EFTR) has a high R0 resection rate and allows for the definitive diagnosis and treatment of selected mucosal and submucosal lesions that are not suitable for conventional resection techniques.
aimTo evaluate the efficacy and safety of EFTR using an over-the-scope clip (OTSC).
methodsThis prospective, single-center, non-randomized clinical trial was conducted at the endoscopy center of Shengjing Hospital of China Medical University. The study included patients aged 18-70 years who had gastric or colorectal submucosal tumors (SMTs) (≤ 20 mm in diameter) originating from the muscularis propria based on endoscopic ultrasound (EUS) and patients who had early-stage gastric or colorectal cancer (≤ 20 mm in diameter) based on EUS and computed tomography. All lesions were treated by EFTR combined with an OTSC for wound closure between November 2014 and October 2016. We analyzed patient demographics, lesion features, histopathological diagnoses, R0 resection (negative margins) status, adverse events, and follow-up results.
resultsA total of 68 patients (17 men and 51 women) with an average age of 52.0 ± 10.5 years (32-71 years) were enrolled in this study, which included 66 gastric or colorectal SMTs and 2 early-stage colorectal cancers. The mean tumor diameter was 12.6 ± 4.3 mm. The EFTR procedure was successful in all cases. The mean EFTR procedure time was 39.6 ± 38.0 min. The mean OTSC defect closure time was 5.0 ± 3.8 min, and the success rate of closure for defects was 100%. Histologically complete resection (R0) was achieved in 67 (98.5%) patients. Procedure-related adverse events were observed in 11 (16.2%) patients. The average post-procedure length of follow-up was 48.2 ± 15.7 mo. There was no recurrence during follow-up.
conclusionEFTR combined with an OTSC is an effective and safe technique for the removal of select subepithelial and epithelial lesions that are not amenable to conventional endoscopic resection techniques.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.