ArticlePersonality and individual differences2021
Big Five Personality and CTRA gene expression: Lack of association in a midlife sample of US adults (MIDUS-Refresher).
Article in Personality and individual differences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Affective reactivity to daily stressors and immune cell gene expression in the MIDUS study.Brain, behavior, and immunity · 2024Article
- Personality traits and mental health care utilization: Longitudinal findings from the MIDUS.Journal of research in personality · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A previous study found that Extraversion and Conscientiousness were associated with increased and decreased expression of a pre-specified set of pro-inflammatory indicator genes. The present study aimed to replicate these findings in a sample of adults from the Refresher Cohort of the Study of Midlife in the United States (MIDUS). Analysis of gene expression composite scores and generalized linear models that took into account the heterogeneity and non-independence of RNA expression across different genes found no significant associations between the pro-inflammatory indicator gene set and the Big Five domains of personality. In addition, there was no significant association between a pre-specified antiviral indicator gene set and the Big Five domains. These findings suggest that relations between Big Five personality and expression of these two immune response indicator gene sets do not consistently appear across samples and may be context-dependent in ways that remain to be elucidated.
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