Evidence map›Paper›PMID 33716255›Full record

ReviewInternal medicine (Tokyo, Japan)2021

Spontaneous Regression of Blastic Plasmacytoid Dendritic Cell Neoplasm Following Sepsis by Serratia marcescens: A Case Report and Literature Review.

Akane Suzuki, Shori Abe, Kaori Koyama, Shinju Suzuki, Munenori Nagao, Masahiro Kobayashi, Jun Nomura, Tomomi Tsutsumi, Tomoki Takeda, Yumiko Oka and 7 more

Open access · diamondAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Akane SuzukiDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Shori AbeDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Kaori KoyamaDivision of Palliative Care, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Shinju SuzukiDivision of Palliative Care, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Munenori NagaoDivision of Palliative Care, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Masahiro KobayashiDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Jun NomuraDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Tomomi TsutsumiDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Tomoki TakedaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Yumiko OkaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Yuko ShirotaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Naruhiko TakasawaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Takao KoderaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Yoko OkitsuDepartment of Clinical Laboratory, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Shinichiro TakahashiDepartment of Clinical Laboratory, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Ryo IchinohasamaDivision of Hematopathology, Tohoku University Hospital, Japan.
Junichi KameokaDivision of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University Hospital, Japan.
Tohoku Medical and Pharmaceutical University Hospital · JPTohoku University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous regression is rare in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN). An 85-year-old man presented with pancytopenia and skin lesions, and the bone marrow exhibited 79.6% CD4+, CD56+, CD123+, and TCL-1+ abnormal cells, with a normal karyotype; he was thus diagnosed with BPDCN. While being followed without chemotherapy, he was admitted due to sepsis induced by Serratia marcescens, which was successfully treated with antibiotics. Notably, his blood cell counts improved, and the skin lesions disappeared. To our knowledge, this is the first reported case of spontaneous regression of BPDCN with a decrease in tumor cells in the bone marrow following sepsis.

Indexed as

Hematologic NeoplasmsMyeloproliferative DisordersSepsisSkin NeoplasmsAged, 80 and overDendritic CellsHumansMaleSerratia marcescensblastic plasmacytoid dendritic cell neoplasmsepsisSerratia marcescensspontaneous regression

Identifiers

PMID33716255
PMCPMC8024952
OpenAlexW3136805268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.