Evidence map›Paper›PMID 33715636›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2021

Retrospective assessment of at-risk myocardium in reperfused acute myocardial infarction patients using contrast-enhanced balanced steady-state free-precession cardiovascular magnetic resonance at 3T with SPECT validation.

Zheng Sun, Qiuhang Zhang, Huan Zhao, Chengxi Yan, Hsin-Jung Yang, Debiao Li, Kuncheng Li, Zhi Liu, Qi Yang, Rohan Dharmakumar

Abstract readValidation Study
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zheng SunDepartment of Radiology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
Qiuhang ZhangDepartment of Radiology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
Huan ZhaoDepartment of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Chengxi YanDepartment of Radiology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
Hsin-Jung YangBiomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, 90048, USA.
Debiao LiBiomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, 90048, USA.
Kuncheng LiDepartment of Radiology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
Zhi LiuDepartment of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. xwyy168@sina.com.
Qi YangDepartment of Radiology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China. yangyangqiqi@gmail.com.ORCID 0000-0002-5773-0456
Rohan DharmakumarBiomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, 90048, USA.

Funding

An Accurate Non-Contrast-Enhanced Cardiac MRI Method for Imaging Chronic Myocardial Infarctions: Technical Developments to Rapid Clinical ValidationR01HL136578 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI LI, DEBIAO · 2017 to 2020
$3.4M
NHLBI NIH HHS R01 HL136578
6 · The paper itself

Abstract

backgroundContrast-enhanced (CE) steady-state free precession (SSFP) CMR at 1.5T has been shown to be a valuable alternative to T2-based methods for the detection and quantifications of area-at-risk (AAR) in acute myocardial infarction (AMI) patients. However, CE-SSFP's capacity for assessment of AAR at 3T has not been investigated. We examined the clinical utility of CE-SSFP and T2-STIR for the retrospective assessment of AAR at 3T with single-photon-emission-computed tomography (SPECT) validation. MATERIALS AND

methodsA total of 60 AMI patients (ST-elevation AMI, n = 44;  non-ST-elevation AMI, n = 16) were recruited into the CMR study between 3 and 7 days post revascularization. All patients underwent T2-STIR, CE-bSSFP and late-gadolinium-enhancement CMR. For validation, SPECT images were acquired in a subgroup of patients (n = 30).

resultsIn 53 of 60 patients (88 %), T2-STIR was of diagnostic quality compared with 54 of 60 (90 %) with CE-SSFP. In a head-to-head per-slice comparison (n = 365), there was no difference in AAR quantified using T2-STIR and CE-SSFP (R

conclusionsAt 3T, both CE-SSFP and T2-STIR can retrospectively quantify the at-risk myocardium with high accuracy.

Indexed as

Magnetic Resonance Imaging, CineTomography, Emission-Computed, Single-PhotonAgedFemaleHumansMaleMiddle AgedMyocardiumNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionPredictive Value of TestsReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsST Elevation Myocardial InfarctionAcute myocardial infarctionArea‐at‐riskCardiovascular magnetic resonanceCE-SSFPSPECT

Identifiers

PMID33715636
PMCPMC7958470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.