Evidence map›Paper›PMID 33715570›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Activation of the β-carbonic anhydrase from the protozoan pathogen

Andrea Angeli, Linda J Urbański, Vesa P Hytönen, Seppo Parkkila, Claudiu T Supuran

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andrea AngeliNeurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.ORCID https://orcid.org/0000-0002-1470-7192
Linda J UrbańskiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Vesa P HytönenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Seppo ParkkilaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0001-7323-8536
Claudiu T SupuranNeurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.ORCID https://orcid.org/0000-0003-4262-0323
Tampere University · FIUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the first activation study of the β-class carbonic anhydrase (CA, EC 4.2.1.1) encoded in the genome of the protozoan pathogen

Indexed as

AminesAmino AcidsCarbonic AnhydrasesDose-Response Relationship, DrugMolecular StructureStructure-Activity RelationshipTrichomonas vaginalisAminesAmino AcidsCarbonic AnhydrasesactivatorAmineamino acidcarbonic anhydraseTrichomonas vaginalis

Identifiers

PMID33715570
PMCPMC7952076
OpenAlexW3135510200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.