ReviewExperimental biology and medicine (Maywood, N.J.)2021
Pathogenesis and brain functional imaging in nocturnal enuresis: A review.
Review in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pharmacological treatment of pediatric nocturnal enuresis: a systematic review and network meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Comparison of the Efficacy of Tolterodine versus Oxybutynin in the Treatment of Children with Desmopressin-Resistant Enuresis: A Randomized Controlled Clinical Trial.Ethiopian journal of health sciences · 2023Trial
- Altered structural and functional brain networks in children with primary nocturnal enuresis: a DTI and resting-state fMRI study.European child & adolescent psychiatry · 2026Article
- Brain microstructure in children with primary monosymptomatic nocturnal enuresis: a diffusion kurtosis imaging study.European journal of pediatrics · 2025Article
- Primary Nocturnal Enuresis and Intelligence Levels in Children: A Meta-Analysis and Systematic Review.Journal of clinical medicine · 2025Review
- Functional connectivity density of brain in children with primary nocturnal enuresis: results from a resting-state fMRI study.European child & adolescent psychiatry · 2025Article
- Relationship Between Obstructive Sleep Apnea and Enuresis in Children: Current Perspectives and Beyond.Nature and science of sleep · 2025Review
- The Resting-State Activities of the Angular Gyrus and the Micturition Desire-Awakening Function in Children With and Without Enuresis.Brain and behavior · 2024Article
- Enuresis in young offenders - a study on prevalence and mental health comorbidity.Frontiers in psychiatry · 2024Article
- Sleep-Disordered Breathing and Its Association with Nocturnal Enuresis at the Primary Schools in Saudi Arabia: A Cross-Sectional Study.Children (Basel, Switzerland) · 2023Article
- Abnormal resting-state functional connectivity of hippocampal subregions in children with primary nocturnal enuresis.Frontiers in psychiatry · 2022Article
- Bibliometric and visual analysis of nocturnal enuresis from 1982 to 2022.Frontiers in pediatrics · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nocturnal enuresis is a common and distressing developmental disease, which may cause various degrees of psychosocial stress and impairment to self-esteem in affected children as well as agitation to their parents or caregivers. Nevertheless, the etiology and pathogenesis of nocturnal enuresis are not understood. Currently, nocturnal enuresis is generally considered a multifactorial disease associated with a complex interaction of somatic, psychosocial, and environmental factors. A variety of postulations have been proposed to explain the occurrence and progression of nocturnal enuresis, including hereditary aberration, abnormal circadian rhythm of antidiuretic hormone secretion during sleep, bladder dysfunction, abnormal sleep, difficulties in arousal, neuropsychological disorders, and maturational delays of the brain. In recent decades, the introduction of functional neuroimaging technologies has provided new approaches for uncovering the mechanisms underlying nocturnal enuresis. The main neuroimaging modalities have included brain morphometry based on structural magnetic resonance imaging (MRI), task-based and event-related functional MRI (fMRI), and resting-state fMRI. The relevant studies have indicated that nocturnal enuresis is associated with functional and structural alterations of the brain. In this review, we briefly summarized the popular hypotheses regarding the pathogenesis of nocturnal enuresis and the current progress of functional neuroimaging studies in examining the underlying mechanisms thereof.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.