Evidence map›Paper›PMID 33715400›Full record

ArticleJournal of the Royal Society, Interface2021

Detection and characterization of chemotaxis without cell tracking.

Jack D Hywood, Gregory Rice, Sophie V Pageon, Mark N Read, Maté Biro

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jack D HywoodSydney Medical School, The University of Sydney, Sydney, Australia.
Gregory RiceDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, Canada.
Sophie V PageonEMBL Australia, Single Molecule Science node, School of Medical Sciences, University of New South Wales, Sydney, Australia.
Mark N ReadSchool of Computer Science & Charles Perkins Centre, University of Sydney, Sydney, Australia.
Maté BiroEMBL Australia, Single Molecule Science node, School of Medical Sciences, University of New South Wales, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swarming has been observed in various biological systems from collective animal movements to immune cells. In the cellular context, swarming is driven by the secretion of chemotactic factors. Despite the critical role of chemotactic swarming, few methods to robustly identify and quantify this phenomenon exist. Here, we present a novel method for the analysis of time series of positional data generated from realizations of agent-based processes. We convert the positional data for each individual time point to a function measuring agent aggregation around a given area of interest, hence generating a functional time series. The functional time series, and a more easily visualized

Indexed as

Cell TrackingChemotactic FactorsChemotaxisAnimalsDiffusionModels, BiologicalMovementChemotactic Factorschemotaxisfunctional data analysisK functionsspatial statisticsswarmingT cells

Identifiers

PMID33715400
PMCPMC8086846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.