Evidence map›Paper›PMID 33715321›Full record

ArticleTurkish journal of obstetrics and gynecology2021

Cervical dysplasia after renal transplantation: A retrospective cohort study.

Ahmet Bilgi, Şevki Göksun Gökulu, Orkun İlgen, Mehmet Kulhan, Seda Akgün Kavurmacı, Hüseyin Toz, Mustafa Coşan Terek

Abstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmet BilgiSelçuk University Faculty of Medicine, Department of Gynaecology and Obstetrics, Konya, Turkey.ORCID 0000-0001-8682-1739
Şevki Göksun GökuluMersin University Faculty of Medicine, Department of Gynaecology and Obstetrics, Mersin, Turkey.ORCID 0000-0002-6581-5716
Orkun İlgenDokuz Eylül University Faculty of Medicine, Department of Gynaecology and Obstetrics, İzmir, Turkey.ORCID 0000-0002-5144-0634
Mehmet KulhanSelçuk University Faculty of Medicine, Department of Gynaecology and Obstetrics, Konya, Turkey.ORCID 0000-0002-5478-7510
Seda Akgün KavurmacıEge University Faculty of Medicine, Department of Gynaecology and Obstetrics, İzmir, Turkey.ORCID 0000-0001-9792-1786
Hüseyin TozEge University Faculty of Medicine, Department of Internal Medicine, İzmir, Turkey.ORCID 0000-0002-2072-3586
Mustafa Coşan TerekEge University Faculty of Medicine, Department of Gynaecology and Obstetrics, İzmir, Turkey.ORCID 0000-0002-0294-2857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSince the first days of organ transplantation, it has been accepted that solid transplant recipients have a high risk of developing cancer. Chronic immunosuppression and environmental factors play a role in cancer development in recipients. In the present study, we tried to evaluate the cumulative incidence of cervical dysplasia after renal transplantation, risk factors for disease development, and the time until high-grade dysplasia occurred. MATERIALS AND

methodsA total of 50 patients with renal transplantation who presented for gynecologic follow-up was included in the study. The medical records of the patients were reviewed until the last clinical visit, their demographic characteristics, transplant history, gynecologic history, and gynecologic examination results (cervical cytology and histology reports) were reviewed.

resultsOf the 50 women in the study population, 29 (58%; 95% confidence interval: 8.8-15.9) developed cervical dysplasia after the first transplant at a median follow-up of 7.8 (range: 4.6-12.9) years. Twenty-one women with benign cervical cytology before transplantation had evidence of low-grade intraepithelial lesions + after transplant (47% of these were within 2 years after transplant). During the follow-up, 8 women (18.2%) were diagnosed as having high-grade intraepithelial lesions + (within 5 years after transplantation).

conclusionRenal transplant patients were found to have higher abnormal cervical cytology and histology rates than the normal population.

Indexed as

cervical dysplasiaImmunosuppressionrenal transplantation

Identifiers

PMID33715321
PMCPMC7962164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.