ArticleJournal of endocrinological investigation2021
Interleukin-6 producing pheochromocytoma/paraganglioma: case series from a tertiary referral centre for pheochromocytomas and paragangliomas.
Article in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Clinical parameters-based machine learning models for predicting intraoperative hemodynamic instability in hypertensive pheochromocytomas and paragangliomas patients.World journal of urology · 2025Article
- Unraveling the genetic basis of metabolic traits and benign adrenal tumors: a comprehensive causal analysis.International journal of clinical and experimental pathology · 2025Article
- IL-6-Producing Pheochromocytoma Associated With Von Hippel Lindau Disease: A Case Report With Literature Review.Cureus · 2024Article
- Interleukin-6-producing paraganglioma as a rare cause of systemic inflammatory response syndrome: a case report.Journal of Yeungnam medical science · 2023Article
- Acquisition of Interleukin-6 Production Ability Over Time With Pheochromocytoma.JCEM case reports · 2023Article
- Pheochromocytoma Multisystem Crisis Complicated by Severe Acute Pancreatitis.Internal medicine (Tokyo, Japan) · 2023Article
- Case Report: A 65-year-old man with paraganglioma accompanied by elevated interleukin-6 levels and KIF1B single gene mutation.Frontiers in endocrinology · 2023Article
- Paraganglioma: An Unexpected Diagnosis in a Patient With Cerebral Venous Sinus Thrombosis and SARS-CoV-2 Infection.Cureus · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn addition to catecholamines, pheochromocytomas and paragangliomas (PPGL) may secrete interleukin-6 (IL-6). IL-6 contributes to the development of unusual symptoms, which may hinder the diagnosis. PATIENTS AND
methodsWe report the clinical course and subsequent treatment of IL-6 producing PPGL in three patients from a single tertiary referral centre for PPGL patients in the Netherlands.
conclusionPPGL combined with persistent elevated inflammatory markers, either in the presence or absence of pyrexia, raised suspicion of IL-6 overproduction in these three patients. Although surgical resection of the tumour is the only curative treatment option, our case series adds to the accumulating evidence that alpha-blockers might be effective in these patients.
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