ArticleNeuroradiology2021
Near-occlusion is difficult to diagnose with common carotid ultrasound methods.
Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Carotid near-occlusion diagnostics and its consequences: A systematic review.European stroke journal · 2026Pooled it
- Short-term risk of recurrent stroke in symptomatic carotid near-occlusion: pooled analysis of three cohort studies.European stroke journal · 2026Article
- Duplex ultrasound in severe carotid stenosis: diagnostic performance for differentiating near-occlusion subtypes from conventional high-grade stenosis.Neuroradiology · 2026Article
- Sex differences in patients with symptomatic carotid stenosis included in three observational cohorts.European stroke journal · 2026Observational
- Carotid near-occlusion diagnostics and its consequences: A systematic review.European stroke journal · 2025Review
- Rule-out and rule-in of carotid near-occlusion using color duplex ultrasound.Neuroradiology · 2025Article
- The pitfalls and challenges in the diagnosis and treatment of patients with carotid near-occlusion: a narrative review.Quantitative imaging in medicine and surgery · 2024Review
- Assessments of arterial and venous phase radiodensity does not improve carotid near-occlusion diagnostics.Scientific reports · 2024Article
- Phase-contrast magnetic resonance imaging of intracranial and extracranial blood flow in carotid near-occlusion.Neuroradiology · 2024Article
- Quantifying Carotid Stenosis: History, Current Applications, Limitations, and Potential: How Imaging Is Changing the Scenario.Life (Basel, Switzerland) · 2024Review
- Diagnosis and treatment of acute isolated proximal internal carotid artery occlusions: a narrative review.Therapeutic advances in neurological disorders · 2022Review
- Defining carotid near-occlusion with full collapse: a pooled analysis.Neuroradiology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the sensitivity and specificity of common carotid ultrasound method for carotid near-occlusion diagnosis.
methodsFive hundred forty-eight patients examined with both ultrasound and CTA within 30 days of each other were analyzed. CTA graded by near-occlusion experts was used as reference standard. Low flow velocity, unusual findings, and commonly used flow velocity parameters were analyzed.
resultsOne hundred three near-occlusions, 272 conventional ≥50% stenosis, 162 <50% stenosis, and 11 occlusions were included. Carotid ultrasound was 22% (95%CI 14-30%; 23/103) sensitive and 99% (95%CI 99-100%; 442/445) specific for near-occlusion diagnosis. Near-occlusions overlooked on ultrasound were found misdiagnosed as occlusions (n = 13, 13%), conventional ≥50% stenosis (n = 65, 63%) and < 50% stenosis (n = 2, 2%). No velocity parameter or combination of parameters could identify the 65 near-occlusions mistaken for conventional ≥50% stenoses with >75% sensitivity and specificity.
conclusionNear-occlusion is difficult to diagnose with commonly used carotid ultrasound methods. Improved carotid ultrasound methods are needed if ultrasound is to retain its position as sole preoperative modality.
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