Observational studyIndian heart journal
Feasibility, safety and outcomes of left bundle branch pacing in octogenarians.
Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Feasibility and Safety of Left Bundle Branch Pacing in Nonagenarians: A Single Center Observational Study.Pacing and clinical electrophysiology : PACE · 2026Observational
- Left Bundle Branch Area Pacing in Older Patients: A New Opportunity?Life (Basel, Switzerland) · 2026Review
- A Meta-Analysis of Clinical and Echocardiographic Outcomes of Physiological Versus Conventional Pacing.Biomedicines · 2025Review
- Review
- Left bundle branch area pacing improving the left atrial outcomes in pace-dependent patients compared with right ventricular outflow tract septal pacing.Clinical cardiology · 2024Article
- Feasibility and safety of left bundle branch area pacing-cardiac resynchronization therapy in elderly patients.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Article
- Physiologic Pacing Targeting the His Bundle and Left Bundle Branch: a Review of the Literature.Current cardiology reports · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesLeft bundle branch pacing (LBBP) provides physiological pacing at low and stable threshold. The safety and efficacy of LBBP in elderly population is unknown. Our study was designed to assess the safety, efficacy and electrophysiological parameters of LBBP in octogenarian (≥80 years) population.
resultsLBBP was successful in 10 out of 11 patients. Mean age 82.1 ± 2.5 yrs. Follow up duration 7.7 months(range4-10). Indication for pacing included atrioventricular (AV) block 5 patients, Left bundle branch block (LBBB) with low ejection fraction (EF) 4 patients, sinus node dysfunction in 1. QRS duration reduced from 145.9 ± 27.7ms to 107.1 ± 9.5ms (p value0.00001) LV ejection fraction increased from 47.6% to 58.4% after LBBP (p value0.017). Pacing threshold was 0.58 ± 0.22 V and sensed R wave 17.35 ± 6.5 mV and it remained stable during follow up. LBBB with low EF patients also showed similar reduction in QRS duration along with improvement in LVEF.
conclusionLBBP is a safe and effective strategy (91% acute success) of physiological pacing in elderly patients. LBBP also provided effective resynchronization therapy in our small group of elderly patients. The pacing parameters remained stable over a period of 10 months follow up.
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