Evidence map›Paper›PMID 33714262›Full record

ArticleWorld journal of surgical oncology2021

Safety and feasibility of total laparoscopic radical resection of Siewert type II gastroesophageal junction adenocarcinoma through the left diaphragm and left thoracic auxiliary hole.

Yun Huang, Gang Liu, Xiumei Wang, Yan Zhang, Guijun Zou, Zhanwei Zhao, Zhen Cao, Huibin Zhao, Xinpu Yuan, Chaojun Zhang

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Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
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10citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clinical practice guidelines for esophagogastric junction cancer: Upper GI Oncology Summit 2023.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yun Huang *General Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Gang Liu *General Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Xiumei WangGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Yan ZhangGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Guijun ZouGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Zhanwei ZhaoGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Zhen CaoGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Huibin ZhaoGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Xinpu YuanGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China.
Chaojun ZhangGeneral Surgery, Sixth Medical Center, PLA General Hospital, Beijing, 100048, China. zcjdlyxzx@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of adenocarcinoma of the esophagogastric junction (AEG) is rising every year; however, the mode of operation for Siewert II AEG is still controversial. Accumulating evidence has shown that transabdominal surgery is better than transthoracic surgery for Siewert II AEG with esophageal invasion < 3 cm. In patients with obesity, a large tumor size, and high transection of the esophagus, the transabdominal esophageal hiatus approach for lower mediastinal lymph node dissection and posterior mediastinal anastomosis is difficult. Thus, total laparoscopic radical resection of Siewert II AEG is carried out through the left diaphragm and left chest auxiliary hole for the optimal surgical field of vision and space. In this prospective study, we assessed the feasibility of carrying out the procedure abdominally through the left diaphragm and auxiliary hole.

methodsTen patients with Siewert II AEG were recruited between April and June 2019. Siewert II AEG was treated by total laparoscopy through the left diaphragm and left chest auxiliary hole. Clinicopathological features, surgical data, and adverse events were collected and analyzed in this prospective study.

resultsThe average duration of the operation was 348 ± 37.52 min, lower mediastinal dissection took 20.6 min, the OrVil anastomosis time was 29.8 min, the time necessary to suture the seromuscular layer through the left thoracic auxiliary hole was 11 min, the safety margin was 3.2 cm, and the total number of lymph nodes dissected was 40.6. The number of lower mediastinal lymph nodes dissected was 6.2. The rate of lymph node metastasis in the N110 group was 9 ± 12.45%, and the average intraoperative blood loss was 170 ± 57.47 mL. No anastomotic leakage or anastomotic stricture occurred after the operation. The time of intestinal function recovery was 2 days, and the first time of enteral nutrition through a jejunal nutrition tube was 2.4 days. No tumor recurrence was found in 10 patients at 1 year postoperatively.

conclusionTotal laparoscopic radical resection through the left diaphragm and left thoracic auxiliary hole for Siewert II AEG patients is feasible and safe. Thus, it may be a good surgical alternative for patients with esophageal tumors invading less than 3 cm.

trial registrationChiCTR, ChiCTR2000034286. Registered 8 July 2020, http://www.chictr.org.cn/showproj.aspx?proj=55866 .

Indexed as

AdenocarcinomaEsophageal NeoplasmsLaparoscopyStomach NeoplasmsDiaphragmEsophagogastric JunctionFeasibility StudiesGastrectomyHumansLymph Node ExcisionPrognosisProspective StudiesRetrospective StudiesAdenocarcinoma of the esophagogastric junctionLaparoscopic surgeryMinimally invasive treatmentSiewert type II

Identifiers

PMID33714262
PMCPMC7956135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.