Evidence map›Paper›PMID 33714250›Full record

ArticleArchives of craniofacial surgery2021

Frequency of anemia and micronutrient deficiency among children with cleft lip and palate: a single-center cross-sectional study from Uttarakhand, India.

Debarati Chattopadhyay, Madhubari Vathulya, Manisha Naithani, Praveen A Jayaprakash, Sarika Palepu, Arkapal Bandyopadhyay, Akshay Kapoor, Uttam Kumar Nath

Open access · diamondAbstract read
In one paragraph

Article in Archives of craniofacial surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Systematic Review of Growth in Young Children With Cleft Lip and/or Cleft Palate From 0 to 24 Months of Age.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Debarati ChattopadhyayDepartment of Burns and Plastic Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Madhubari VathulyaDepartment of Burns and Plastic Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Manisha NaithaniDepartment of Biochemistry, All India Institute of Medical Sciences, Rishikesh, India.
Praveen A JayaprakashDepartment of Burns and Plastic Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Sarika PalepuDepartment of Community Medicine, Government Medical College, Srinagar, India.
Arkapal BandyopadhyayDepartment of Pharmacology, All India Institute of Medical Sciences, Rishikesh, India.
Akshay KapoorDepartment of Burns and Plastic Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Uttam Kumar NathDepartment of Medical Oncology Hematology, All India Institute of Medical Sciences, Rishikesh, India.
All India Institute of Medical Sciences Rishikesh · INGovernment Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with cleft lip and/or palate can be undernourished due to feeding difficulties after birth. A vicious cycle ensues where malnutrition and low body weight precludes the child from having the corrective surgery, in the absence of which the child fails to gain weight. This study aimed to identify the proportion of malnutrition, including the deficiency of major micronutrients, namely iron, folate and vitamin B12, in children with cleft lip and/or palate and thus help in finding out what nutritional interventions can improve the scenario for these children.

methodsAll children less than 5 years with cleft lip and/or cleft palate attending our institute were included. On their first visit, following were recorded: demographic data, assessment of malnutrition, investigations: complete blood count and peripheral blood film examination; serum albumin, ferritin, iron, folate, and vitamin B12 levels.

resultsEighty-one children with cleft lip and/or palate were included. Mean age was 25.37± 21.49 months (range, 3-60 months). In 53% of children suffered from moderate to severe wasting, according to World Health Organization (WHO) classification. Iron deficiency state was found in 91.6% of children. In 35.80% of children had vitamin B12 deficiency and 23.45% had folate deficiency. No correlation was found between iron deficiency and the type of deformity.

conclusionIron deficiency state is almost universally present in children with cleft lip and palate. Thus, iron and folic acid supplementation should be given at first contact to improve iron reserve and hematological parameters for optimum and safe surgery.

Indexed as

AnemiaCleft lipCleft palateIron deficiency

Identifiers

PMID33714250
PMCPMC7968976
OpenAlexW3135263399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.