Evidence map›Paper›PMID 33713587›Full record

ArticlePediatric pulmonology2021

Characteristics of infants or children presenting to outpatient bronchopulmonary dysplasia clinics in the United States.

Joseph M Collaco, Amit Agarwal, Eric D Austin, Lystra P Hayden, Khanh Lai, Jonathan Levin, Winston M Manimtim, Paul E Moore, Catherine A Sheils, Michael C Tracy and 8 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Interdisciplinary clinical bronchopulmonary dysplasia programs: development, evolution, and maturation.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  5. The Developmental Origins of Asthma and COPD.Annual review of physiology · 2026
    Review
  6. Toward precision for bronchopulmonary dysplasia: Moving past current definitions.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Observational
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 2 countries.

Joseph M CollacoEudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-2581-4372
Amit AgarwalDivision of Pediatric Pulmonary and Sleep Medicine, Arkansas Children's Hospital, UAMS College of Medicine, Little Rock, Arkansas, USA.
Eric D AustinDivision of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-1709-9022
Lystra P HaydenDivision of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Khanh LaiDivision of Pediatric Pulmonary and Sleep Medicine, University of Utah, Salt Lake City, Utah, USA.
Jonathan LevinDivision of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Winston M ManimtimDivision of Neonatology, Children's Mercy-Kansas City and University of Missouri-Kansas City, Kansas City, Missouri, USA.
Paul E MooreDivision of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-5123-207X
Catherine A SheilsDivision of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Michael C TracySection on Asthma and Sleep Medicine, Division of Pediatric Pulmonary, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-0474-1669
Stamatia AlexiouDivision of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Christopher D BakerDivision of Pediatrics-Pulmonary Medicine, University of Colorado, Denver, Colorado, USA.ORCID 0000-0002-1171-563X
A Ioana CristeaSection on Allergy and Sleep Medicine, Division of Pediatric Pulmonology, Riley Children's Hospital and Indiana University, Indianapolis, Indiana, USA.ORCID 0000-0002-9206-2190
Julie L FierroDivision of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9454-5954
Lawrence M RheinDivision of Neonatal-Perinatal Medicine/Pediatric Pulmonology, University of Massachusetts, Worcester, Massachusetts, USA.ORCID 0000-0001-5703-8833
Natalie VillafrancoDivision of Pulmonary Medicine, Texas Children's Hospital and Baylor University, Houston, Texas, USA.
Leif D NelinDivision of Neonatology, Nationwide Children's Hospital and Ohio State University, Columbus, Ohio, USA.
Sharon A McGrath-MorrowDivision of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-1576-5394
Boston Children's Hospital · USChildren's Hospital of Philadelphia · USVanderbilt University Medical Center · USArkansas Children's Hospital · USBaylor University · USChildren's Mercy Hospital · USJohns Hopkins University · USNationwide Children's Hospital · USRiley Hospital for Children · USStanford Medicine · USUniversity of Colorado Hospital · USUniversity of Massachusetts Chan Medical School · USUniversity of Utah · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Resolution of Diffuse Inflammatory Lung Injury in Neonatal MiceR01HL114800 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MCGRATH-MORROW, SHARON ANN · 2013 to 2021
$3.3M
Genetic Epidemiology of Respiratory Function in Former Preterm ChildrenK23HL136851 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HAYDEN, LYSTRA P. · 2018 to 2022
$969k
NHLBI NIH HHS K23 HL136851NHLBI NIH HHS R01 HL114800NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

introductionBronchopulmonary dysplasia (BPD) is a common respiratory sequelae of preterm birth, for which longitudinal outpatient data are limited. Our objective was to describe a geographically diverse outpatient cohort of former preterm infants followed in BPD-disease specific clinics.

methodsSeven BPD specialty clinics contributed data using standardized instruments to this retrospective cohort study. Inclusion criteria included preterm birth (<37 weeks) and respiratory symptoms or needs requiring outpatient follow-up.

resultsA total of 413 preterm infants and children were recruited (mean age: 2.4 ± 2.7 years) with a mean gestational age of 27.0 ± 2.8 weeks and a mean birthweight of 951 ± 429 grams of whom 63.7% had severe BPD. Total, 51.1% of subjects were nonwhite. Severe BPD was not associated with greater utilization of acute care/therapies compared to non-severe counterparts. Of children with severe BPD, differences in percentage of those on any home respiratory support (p = .001), home positive pressure ventilation (p = .003), diuretics (p < .001), inhaled corticosteroids (p < .001), and pulmonary vasodilators (p < .001) were found between centers, however no differences in acute care use were observed. DISCUSSION: This examination of a multicenter collaborative registry of children born prematurely with respiratory disease demonstrates a diversity of management strategies among geographically distinct tertiary care BPD centers in the United States. This study reveals that the majority of children followed in these clinics were nonwhite and that neither variation in management nor severity of BPD at 36 weeks influenced outpatient acute care utilization. These findings suggest that post-neonatal intensive care unit factors and follow-up may modify respiratory outcomes in BPD, possibly independently of severity.

Indexed as

Bronchopulmonary DysplasiaPremature BirthChildChild, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureOutpatientsPregnancyRetrospective StudiesUnited Statesbronchopulmonary dysplasiachronic lung diseaseoutpatientprematurity

Identifiers

PMID33713587
PMCPMC8137590
OpenAlexW3136702060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.