Evidence map›Paper›PMID 33713285›Full record

ArticleInternal and emergency medicine2021

Admission hyperglycemia and all-cause mortality in diabetic and non-diabetic patients with acute myocardial infarction: a tertiary center analysis.

João André Ferreira, Rui Miguel Baptista, Sílvia Reis Monteiro, Francisco Manuel Gonçalves, Pedro Filipe Monteiro, Lino Manuel Gonçalves

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  15. Acute Hyperglycemia-Induced Injury in Myocardial Infarction.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João André FerreiraDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal. joaoaferreira29@gmail.com.ORCID http://orcid.org/0000-0002-4732-5545
Rui Miguel BaptistaDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.
Sílvia Reis MonteiroDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.
Francisco Manuel GonçalvesDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.
Pedro Filipe MonteiroDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.
Lino Manuel GonçalvesDepartment of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Admission hyperglycemia (AH) is associated with worse prognosis in patients with acute myocardial infarction (AMI). Controversy remains whether the impact of AH differs among patients previously diagnosed with diabetes mellitus (DM). We retrospectively evaluated consecutive patients admitted in a coronary care unit with AMI, from 2006 to 2014. Patients were divided into 4 groups: patients without known DM with admission glycemia (AG) ≤ 143 mg/dL (group 1), patients without known DM with AG > 143 mg/dL (group 2), known DM with AG ≤ 213 mg/dL (group 3), and known DM with AG > 213 mg/dL (group 4). Primary outcome was defined as all-cause mortality during follow-up. A total of 2768 patients were included: 1425 in group 1, 426 in group 2, 593 in group 3, and 325 in group 4. After a median follow-up of 5.6 years, 1047 (37.8%) patients reached primary outcome. After multivariate analysis, group 4 was associated with the worst prognosis (HR 3.103, p < 0.001) followed by group 3 (HR 1.639, p = 0.002) and group 2 (HR 1.557, p = 0.039), when compared to group 1. When groups were stratified by type of AMI, patients in group 2 had a worse prognosis than patients in group 3 in the case of non-ST-segment elevation AMI. AH is associated with higher all-cause mortality in patients with AMI, irrespective of previous diabetic status.

Indexed as

AgedAged, 80 and overBlood GlucoseFemaleHospital MortalityHumansHyperglycemiaMaleMiddle AgedMyocardial InfarctionPatient AdmissionPrognosisProportional Hazards ModelsRetrospective StudiesRisk FactorsTertiary Care CentersBlood GlucoseAcute myocardial infarctionAdmission hyperglycemiaDiabetes mellitusPrognosis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.