Evidence map›Paper›PMID 33713272›Full record

ArticleGeneral thoracic and cardiovascular surgery2021

Multiple small tumor formation on both surfaces of the aortic valve cusps in Epstein-Barr virus-associated T/NK-cell lymphoproliferative disease: a case report.

Ryuta Tai, Hiroyuki Irie, Yusuke Kinugasa, Hideki Teshima, Masahiko Ikebuchi, Keiko Kaneko, Nobuhiro Miyazaki, Hideaki Enzan, Tadashi Yoshino

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in General thoracic and cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ryuta TaiCardiovascular Surgery, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan. riu_g_10@yahoo.co.jp.ORCID http://orcid.org/0000-0003-3219-6661
Hiroyuki IrieCardiovascular Surgery, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Yusuke KinugasaCardiovascular Surgery, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Hideki TeshimaCardiovascular Surgery, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Masahiko IkebuchiCardiovascular Surgery, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Keiko KanekoNeurology, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Nobuhiro MiyazakiRadiology, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Hideaki EnzanDiagnostic Pathology, Chikamori Hospital, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan.
Tadashi YoshinoDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.
Chikamori Hospital · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 41-year-old woman presented acute cerebral infarction. Transesophageal echocardiography revealed multiple masses only on both surfaces of the aortic valve cusps. There was no primary lesion outside the heart according to various examinations. After treatment for cerebral infarction, we replaced the aortic valve instead of preservation because the intraoperative histological examination reported that malignancy was highly suspected. Contrary to the rapid frozen section diagnosis, histological and immunohistochemical examinations failed to exhibit malignancy. The tumors were composed of atypical large lymphoid cells and they were assessed to be related to T-/natural killer-cells. Furthermore, Epstein-Barr virus related markers were also positive. Her three-year postoperative course was uneventful without chemotherapy. We report an extremely rare case of Epstein-Barr virus-associated T-/natural killer-cell lymphoproliferative disease which formed multiple small tumors on both surfaces of the aortic valve.

Indexed as

Epstein-Barr Virus InfectionsLymphoproliferative DisordersAdultAortic ValveFemaleHerpesvirus 4, HumanHumansKiller Cells, NaturalAortic valveCardiac tumorEpstein–Barr virusLymphoproliferative disease

Identifiers

PMID33713272
PMCPMC8131301
OpenAlexW3134893151

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.