Evidence map›Paper›PMID 33713204›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2021

Prevention of incisional hernia at the site of stoma closure with different reinforcing mesh types: a systematic review and meta-analysis.

Roberto Peltrini, Nicola Imperatore, Gaia Altieri, Simone Castiglioni, Maria Michela Di Nuzzo, Luciano Grimaldi, Michele D'Ambra, Ruggero Lionetti, Umberto Bracale, Francesco Corcione

Open access · hybridAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Cost-effectiveness of selective prophylactic mesh placement after stoma closure.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Pooled it
  2. Type of mesh and wall plane in prophylactic mesh after stoma closure: A network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Pooled it
  3. Reversal of stoma with biosynthetic mesh fascial reinforcement: a systematic review and meta-analysis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
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  17. Simultaneous incisional hernia repair and colorectal surgery: one or two-step procedure?Hernia : the journal of hernias and abdominal wall surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Roberto PeltriniDepartment of Public Health, University of Naples Federico II, Naples, Italy. roberto.peltrini@gmail.com.ORCID http://orcid.org/0000-0003-0445-2269
Nicola ImperatoreDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Gaia AltieriDepartement of Gastroenterological, Endocrine-Metabolic and Nephrourological Sciences, Università Cattolica del Sacro Cuore, Rome, Italy.
Simone CastiglioniDepartment of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio Chieti-Pescara, Chieti, Italy.
Maria Michela Di NuzzoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Luciano GrimaldiDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Michele D'AmbraDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Ruggero LionettiDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Umberto BracaleDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Francesco CorcioneDepartment of Public Health, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · ITFederico II University Hospital · ITOspedale Antonio Cardarelli · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate safety and efficacy of a mesh reinforcement following stoma reversal to prevent stoma site incisional hernia (SSIH) and differences across the prostheses used.

methodsA systematic search of PubMed/MEDLINE, EMBASE, SCOPUS and Cochrane databases was conducted to identify comparative studies until September 2020. A meta-analysis of postoperative outcomes and a network meta-analysis for a multiple comparison of the prostheses with each other were performed.

resultsSeven studies were included in the analysis (78.4% ileostomy and 21.6% colostomy) with a total of 1716 patients with (n = 684) or without (n = 1032) mesh. Mesh placement was associated with lower risk of SSIH (7.8%vs18.1%, OR0.266,95% CI 0.123-0.577, p < 0.001) than no mesh procedures but also with a longer operative time (SMD 0.941, 95% CI 0.462-1.421, p < 0.001). There was no statistically significant difference in terms of Surgical Site infection (11.5% vs 11.1%, OR 1.074, 95% CI 0.78-1.48, p = 0.66), seroma formation (4.4% vs 7.1%, OR 1.052, 95% CI 0.64-1.73, p = 0.84), anastomotic leakage (3.7% vs 2.7%, OR 1.598, 95% CI 0.846-3.019, p = 0.149) and length of stay (SMD - 0.579,95% CI - 1.261 to 0.102, p = 0.096) between mesh and no mesh groups. Use of prosthesis was associated with a significant lower need for a reoperation than no mesh group (8.1% vs 12.1%, OR 0.332, 95% CI 0.119-0.930, p = 0.036). Incidence of seroma is lower with biologic than polypropylene meshes but they showed a trend towards poor results compared with polypropylene or biosynthetic meshes.

conclusionDespite longer operative time, mesh prophylactic reinforcement at the site of stoma seems a safe and effective procedure with lower incidence of SSIH, need for reoperation and comparable short-term outcomes than standard closure technique. A significant superiority of a specific mesh type was not identified.

Indexed as

Incisional HerniaSurgical StomasHerniorrhaphyHumansProstheses and ImplantsSurgical MeshBiologic meshIncisional herniaPreventionStoma reversalSynthetic mesh

Identifiers

PMID33713204
PMCPMC8197707
OpenAlexW3135256570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.