Evidence map›Paper›PMID 33713190›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Risk-stratification of thyroid nodules examined by

Peter Bakkegaard, Stefano Christian Londero, Steen Joop Bonnema, Viveque Egsgaard Nielsen, Marie Louise Jespersen, Kristine Zøylner Swan

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02150772 (Shear Wave Elastography in the Diagnosis and Risk-stratification of Thyroid Nodules - a Prospective Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02150772 nacompletednot on this map

Shear Wave Elastography in the Diagnosis and Risk-stratification of Thyroid Nodules - a Prospective Study

TypeinterventionalSponsorUniversity of AarhusRan2014 to 2016Enrolled308ConditionsThyroid NoduleArmsShear Wave Elastography (SWE)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peter BakkegaardDepartment of Otorhinolaryngology Head- and Neck Surgery, Aarhus University Hospital (AUH), Aarhus, Denmark.
Stefano Christian LonderoDepartment of Otorhinolaryngology Head- and Neck Surgery, Aarhus University Hospital (AUH), Aarhus, Denmark.
Steen Joop BonnemaDepartment of Endocrinology, Odense University Hospital (OUH), Odense, Denmark.
Viveque Egsgaard NielsenDepartment of Otorhinolaryngology Head- and Neck Surgery, OUH, Odense, Denmark.
Marie Louise JespersenDepartment of Pathology, AUH, Aarhus, Denmark.
Kristine Zøylner SwanDepartment of Otorhinolaryngology Head- and Neck Surgery, Aarhus University Hospital (AUH), Aarhus, Denmark. kristineswan@dadlnet.dk.ORCID http://orcid.org/0000-0003-2958-5279
Aarhus University Hospital · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe risk of malignancy (ROM) in FDG-avid thyroid incidentalomas varies between studies, which may be contributed by discordance between the anatomical localization depicted on

methodsThirty-two patients referred to thyroid surgery were prospectively included.

resultsForty thyroid nodules were included. Malignancy was identified in 10 of 28 PET-positive nodules and in 1 of 12 PET-negative nodules, resulting in a ROM of 36% and 8%, respectively. A Hurtle cell neoplasm was found in 50% of patients with a benign nodule and a PET-positive scan. One PET-negative nodule represented a papillary microcarcinoma. In PET-positive nodules, hypoechogenicity, irregular margins, and pathological lymph nodes on thyroid ultrasonography were characteristics associated with malignancy.

conclusionsIn this study-ensuring anatomical congruity between PET-findings and the histopathological examination-the risk of malignancy in PET-positive thyroid nodules was 36%. A low ROM was seen in thyroid nodules without suspicious ultrasonographic findings, independent of the TRIAL REGISTRATION NUMBER: NCT02150772 registered 14th of April 2014.

Indexed as

Thyroid NeoplasmsThyroid NoduleFluorodeoxyglucose F18HumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesSensitivity and SpecificityUltrasonographyFluorodeoxyglucose F1818FDG-PET/CTDiagnosisThyroid cancerThyroid nodule

Identifiers

PMID33713190
OpenAlexW3135586600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.