Evidence map›Paper›PMID 33713174›Full record

ArticleEuropean radiology2021

Improved coronary calcification quantification using photon-counting-detector CT: an ex vivo study in cadaveric specimens.

Mårten Sandstedt, Jeffrey Marsh, Kishore Rajendran, Hao Gong, Shengzhen Tao, Anders Persson, Shuai Leng, Cynthia McCollough

Abstract read
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Computed Tomography in Infectious Endocarditis.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Journal of medical imaging (Bellingham, Wash.) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mårten SandstedtCenter for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.
Jeffrey MarshDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Kishore RajendranDepartment of Radiology, Mayo Clinic, Rochester, MN, USA. rajendran.kishore@mayo.edu.ORCID http://orcid.org/0000-0002-8314-3642
Hao GongDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Shengzhen TaoDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Anders PerssonCenter for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Cynthia McColloughDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.

Funding

Photon-Counting Spectral CT to Reduce Dose and Detect Early Vascular DiseaseR01EB016966 · NIBIB · MAYO CLINIC ROCHESTER · PI MCCOLLOUGH, CYNTHIA H · 2013 to 2017
$5.1M
EXTRAMURAL RES FACIL IMPROVEMENT PROG: POLYCYSTIC KIDNEY DISEASE, RENAL STUDIES,C06RR018898 · NCRR · MAYO CLINIC · PI BURNETT, JOHN C · 2004 to 2004
$2.3M
NCRR NIH HHS C06 RR018898NIBIB NIH HHS R01 EB016966
6 · The paper itself

Abstract

objectivesTo compare the accuracy of coronary calcium quantification of cadaveric specimens imaged from a photon-counting detector (PCD)-CT and an energy-integrating detector (EID)-CT.

methodsExcised coronary specimens were scanned on a PCD-CT scanner, using both the PCD and EID subsystems. The scanning and reconstruction parameters for EID-CT and PCD-CT were matched: 120 kV, 9.3-9.4 mGy CTDI

resultsThe volume measurements in 12/13 calcifications followed a similar trend: EID-D50 > PCD-D50 > PCD-D60 > micro-CT. The median calcified volumes in EID-D50, PCD-D50, PCD-D60, and micro-CT were 22.1 (IQR 10.2-64.8), 21.0 (IQR 9.0-56.5), 18.2 (IQR 8.3-49.3), and 14.6 (IQR 5.1-42.4) mm

conclusionThe PCT-CT system quantified coronary calcifications more accurately than EID-CT, and a sharp PCD-CT kernel further improved the accuracy. The PCD-CT images exhibited lower noise than the EID-CT images. KEY POINTS: • High spatial resolution offered by PCD-CT reduces partial volume averaging and consequently leads to better morphological depiction of coronary calcifications. • Improved quantitative accuracy for coronary calcification volumes could be achieved using high-resolution PCD-CT compared to conventional EID-CT. • PCD-CT images exhibit lower image noise than conventional EID-CT at matched radiation dose and reconstruction kernel.

Indexed as

PhotonsTomography, X-Ray ComputedCadaverHumansPhantoms, ImagingTomography Scanners, X-Ray ComputedArtifactsCadaverCoronary artery diseaseX-ray tomography

Identifiers

PMID33713174
PMCPMC8380662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.