Evidence map›Paper›PMID 33713148›Full record

ArticleArchives of toxicology2021

N6-methyladenosine reader YTHDC2 and eraser FTO may determine hepatocellular carcinoma prognoses after transarterial chemoembolization.

Jiandong Liu, Dongyang Wang, Jianyuan Zhou, Leirong Wang, Nasha Zhang, Liqing Zhou, Jiajia Zeng, Jibing Liu, Ming Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 32 citations in OpenAlex.

  1. The mCells · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Decoding mGenes & diseases · 2024
    Review
  8. Article
  9. NJournal of translational internal medicine · 2024
    Article
  10. RNA m6A methylation regulators in liver cancer.Cancer cell international · 2024
    Review
  11. Review
  12. The Allelic Expression of RNA Editing GenePharmacogenomics and personalized medicine · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Role of m6A writers, erasers and readers in cancer.Experimental hematology & oncology · 2022
    Review
  17. An NAnnals of translational medicine · 2022
    Article
  18. Review
  19. Review
  20. Genome-Wide Identification ofFrontiers in endocrinology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiandong Liu *Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.
Dongyang Wang *Department of Endoscopy, Shandong Cancer Hospital and Institute, Jinan, Shandong, China.
Jianyuan Zhou *Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong Province, China.
Leirong WangShandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.
Nasha ZhangDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, Shandong, China.
Liqing ZhouDepartment of Radiation Oncology, Huaian No. 2 Hospital, Huaian, Jiangsu, China.
Jiajia ZengShandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.
Jibing LiuDepartment of Intervention Surgery, Shandong Cancer Hospital and Institute, Jinan, 250117, Shandong, China. liujibing19751028@163.com.
Ming YangShandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China. aaryoung@yeah.net.ORCID http://orcid.org/0000-0003-0310-5839
Shandong Tumor Hospital · CNHuaian First People’s Hospital · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transarterial chemoembolization (TACE) has significantly improved overall survival (OS) of unresectable hepatocellular carcinoma (HCC) patients. Unfortunately, a portion of patients show no therapeutic responses to TACE. N6-methyladenosine (m

Indexed as

AdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAsian PeopleCarcinoma, HepatocellularChemoembolization, TherapeuticCohort StudiesGenotypeHumansLiver NeoplasmsPolymorphism, Single NucleotidePrognosisProportional Hazards ModelsRNA HelicasesTreatment OutcomeAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanN-methyladenosineRNA HelicasesYTHDC2 protein, humanFTOHepatocellular carcinomam6ATACEYTHDC2

Identifiers

PMID33713148
OpenAlexW3135026581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.