ArticleJournal of computational neuroscience2021
The unknown but knowable relationship between Presaccadic Accumulation of activity and Saccade initiation.
Article in Journal of computational neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Spatial and Temporal Factors Influencing Fixational Saccades.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neural Control of Vergence and Ocular Accommodation.Annual review of vision science · 2025Review
- Factorial variation of saccade vigor with dual decision processes.bioRxiv : the preprint server for biology · 2025Article
- Eccentricity-dependent saccadic reaction time: The roles of foveal magnification and attentional orienting.iScience · 2025Article
- Non-decision time: The Higgs Boson of decision.Psychological review · 2025Article
- The gated cascade diffusion model: An integrated theory of decision making, motor preparation, and motor execution.Psychological review · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The goal of this short review is to call attention to a yawning gap of knowledge that separates two processes essential for saccade production. On the one hand, knowledge about the saccade generation circuitry within the brainstem is detailed and precise - push-pull interactions between gaze-shifting and gaze-holding processes control the time of saccade initiation, which begins when omnipause neurons are inhibited and brainstem burst neurons are excited. On the other hand, knowledge about the cortical and subcortical premotor circuitry accomplishing saccade initiation has crystalized around the concept of stochastic accumulation - the accumulating activity of saccade neurons reaching a fixed value triggers a saccade. Here is the gap: we do not know how the reaching of a threshold by premotor neurons causes the critical pause and burst of brainstem neurons that initiates saccades. Why this problem matters and how it can be addressed will be discussed. Closing the gap would unify two rich but curiously disconnected empirical and theoretical domains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.