Evidence map›Paper›PMID 33712929›Full record

ReviewParasitology research2021

Small ruminants and zoonotic cryptosporidiosis.

Yaqiong Guo, Na Li, Una Ryan, Yaoyu Feng, Lihua Xiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Parasitology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. The global prevalence ofParasitology · 2022
    Pooled it
  3. Article
  4. Prevalence and molecular characterisation ofInternational journal for parasitology. Parasites and wildlife · 2026
    Article
  5. Article
  6. Review
  7. Development of Multiplex Real-Time Quantitative PCR for the Detection ofAnimals : an open access journal from MDPI · 2026
    Article
  8. Molecular Characterization and Zoonotic Potential ofTransboundary and emerging diseases · 2026
    Article
  9. Molecular biology of the cell · 2025
    Article
  10. Prevalence and molecular characterization ofFood and waterborne parasitology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Veterinary world · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yaqiong GuoCenter for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Na LiCenter for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Una RyanHarry Butler Institute, Vector- and Water-Borne Pathogen Research Group, Murdoch University, Murdoch, Western Australia, 6150, Australia.
Yaoyu FengCenter for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. yyfeng@scau.edu.cn.
Lihua XiaoCenter for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. lxiao1961@gmail.com.ORCID http://orcid.org/0000-0001-8532-2727
South China Agricultural University · CNMurdoch University · AU

Funding

Guangdong Major Project of Basic and Applied Basic Research 2020B0301030007Guangdong Province Introduction of Innovative R&D Team 2019KCXTD001Higher Education Discipline Innovation Project D20008National Natural Science Foundation of China 31820103014National Natural Science Foundation of China U1901208
6 · The paper itself

Abstract

Sheep and goats are commonly infected with three Cryptosporidium species, including Cryptosporidium parvum, Cryptosporidium ubiquitum, and Cryptosporidium xiaoi, which differ from each in prevalence, geographic distribution, and public health importance. While C. parvum appears to be a dominant species in small ruminants in European countries, its occurrence in most African, Asian, and American countries appear to be limited. As a result, zoonotic infections due to contact with lambs and goat kids are common in European countries, leading to frequent reports of outbreaks of cryptosporidiosis on petting farms. In contrast, C. xiaoi is the dominant species elsewhere, and mostly does not infect humans. While C. ubiquitum is another zoonotic species, it occurs in sheep and goats at much lower frequency. Host adaptation appears to be present in both C. parvum and C. ubiquitum, consisting of several subtype families with different host preference. The host-adapted nature of C. parvum and C. ubiquitum has allowed the use of subtyping tools in tracking infection sources. This has led to the identification of geographic differences in the importance of small ruminants in epidemiology of human cryptosporidiosis. These tools have also been used effectively in linking zoonotic transmission of C. parvum between outbreak cases and the suspected animals. Further studies should be directly elucidating the reasons for differences in the distribution and public health importance of major Cryptosporidium species in sheep and goats.

Indexed as

CryptosporidiosisCryptosporidiumGoat DiseasesSheep DiseasesAnimalsFecesGenotypeGoatsSheepCryptosporidiosisCryptosporidiumGoatMolecular epidemiologyOne healthSheepZoonosis

Identifiers

PMID33712929
OpenAlexW3134945737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.