Evidence map›Paper›PMID 33712877›Full record

Observational studyOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021

Regional and gender-specific analyses give new perspectives for secular trend in hip fracture incidence.

S-R Pekonen, J Kopra, H Kröger, T Rikkonen, R Sund

Abstract readObservational Study
In one paragraph

Observational study in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  12. Hospitalizations for major osteoporotic fractures in Switzerland: a long-term trend analysis between 1998 and 2018.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  13. Article
  14. Relatively low and moderate pre-fracture serum 25-hydroxyvitamin D levels associated with the highest survival in elderly hip fracture patients in Finland: a minimum 3-year follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  15. Where's the break? Critique of radiographic vertebral fracture diagnostic methods.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S-R PekonenSchool of Medicine, University of Eastern Finland, Kuopio, Finland. sallarp@student.uef.fi.ORCID http://orcid.org/0000-0002-1917-7880
J KopraKuopio Musculoskeletal Research Unit, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0002-8304-8936
H KrögerKuopio Musculoskeletal Research Unit, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0003-4245-8186
T RikkonenKuopio Musculoskeletal Research Unit, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0001-5948-1222
R SundKuopio Musculoskeletal Research Unit, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0002-6268-8117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we found that regional disparity in incidence of hip fractures has converged. Also, annual hip fracture risk ratios between genders have systematically diminished over time.

introductionSeveral studies have reported secular trends in hip fracture incidence, but knowledge about the possible causes is limited. We studied potential explanations by examining spatio-temporal epidemiology of the fractures and estimating relative risks between genders.

methodsThis observational study was based on all inpatient hospital discharges in 1972-2018 in Finland. We divided the data by gender, 5-year age groups and Finnish sub-regions and estimated gender and age standardized spatio-temporal rates of hip fractures by using a Bayesian age-period-cohort model.

resultsIn 1972, women's hip fracture incidence was 1.2-1.3 times higher in western and coastal Finland compared to eastern and inland areas. Also, women had approximately 1.7 times higher average risk to get a hip fracture compared to men. Today, the hip fracture differences between the areas have converged to insignificant and the relative risk between genders has diminished to 1.2. Age-specific relative risks indicate greater hip fracture risk for younger men and older women, and the women's risk increases beyond the risk of men at age 65 which is ten years later than in the beginning of the study period.

conclusionIncidence of hip fracture has converged significantly between regions and genders. Especially factors related with socioeconomic development and increased frailty and longevity seem to be important. The hip fracture incidence rate ratio between women and men has systematically decreased in time, and more attention should be paid to hip fracture risk in men in the future.

Indexed as

Hip FracturesAgedBayes TheoremChildFemaleForecastingHumansIncidenceMaleRiskEpidemiologyFracture preventionFracture risk assessmentGeneral population studiesOrthopaedics

Identifiers

PMID33712877
PMCPMC8387269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.