Evidence map›Paper›PMID 33712728›Full record

ArticleCommunications biology2021

Pocket MUSE: an affordable, versatile and high-performance fluorescence microscope using a smartphone.

Yehe Liu, Andrew M Rollins, Richard M Levenson, Farzad Fereidouni, Michael W Jenkins

Open access · goldAbstract readComparative StudyVideo-Audio Media
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 50 citations in OpenAlex.

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  12. Current Landscape of Advanced Imaging Tools for Pathology Diagnostics.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2024
    Review
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  20. CRISPR-Enhanced Hydrogel Microparticles for Multiplexed Detection of Nucleic Acids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yehe LiuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.ORCID 0000-0002-0221-5676
Andrew M RollinsDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.
Richard M LevensonDepartment of Pathology and Laboratory Medicine, University of California Davis Medical Center, Sacramento, CA, USA.ORCID 0000-0002-0112-6823
Farzad FereidouniDepartment of Pathology and Laboratory Medicine, University of California Davis Medical Center, Sacramento, CA, USA.
Michael W JenkinsDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA. wmj5@case.edu.
Case Western Reserve University · USUniversity of California Davis Medical Center · US

Funding

3D Microscopy with Ultraviolet Surface Excitation (3D-MUSE)R01EB028635 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI LEVENSON, RICHARD M., WILSON, DAVID LYNN · 2019 to 2023
$2.7M
Imaging and informatics techniques to spatially map tumor-associated collagen: novel cancer diagnostic tools (2 of 2)R33CA202881 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEVENSON, RICHARD M. · 2017 to 2019
$1.3M
NCI NIH HHS R33 CA202881NIBIB NIH HHS R01 EB028635
6 · The paper itself

Abstract

Smartphone microscopes can be useful tools for a broad range of imaging applications. This manuscript demonstrates the first practical implementation of Microscopy with Ultraviolet Surface Excitation (MUSE) in a compact smartphone microscope called Pocket MUSE, resulting in a remarkably effective design. Fabricated with parts from consumer electronics that are readily available at low cost, the small optical module attaches directly over the rear lens in a smartphone. It enables high-quality multichannel fluorescence microscopy with submicron resolution over a 10× equivalent field of view. In addition to the novel optical configuration, Pocket MUSE is compatible with a series of simple, portable, and user-friendly sample preparation strategies that can be directly implemented for various microscopy applications for point-of-care diagnostics, at-home health monitoring, plant biology, STEM education, environmental studies, etc.

Indexed as

Mobile ApplicationsSmartphoneAnimalsBacteriaEquipment DesignFluorescent Antibody TechniqueHumansImage Processing, Computer-AssistedMiceMicroscopy, FluorescenceMouth MucosaPlantsReproducibility of ResultsSpecimen HandlingStaining and Labeling

Identifiers

PMID33712728
PMCPMC7955119
OpenAlexW3134769625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.