Evidence map›Paper›PMID 33712630›Full record

ArticleScientific reports2021

Ketone body 3-hydroxybutyrate as a biomarker of aggression.

A M Whipp, E Vuoksimaa, T Korhonen, R Pool, A But, L Ligthart, F A Hagenbeek, M Bartels, L H Bogl, L Pulkkinen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

A M WhippInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. alyce.whipp@helsinki.fi.
E VuoksimaaInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
T KorhonenInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
R PoolDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
A ButClinicum, Department of Public Health, University of Helsinki, Helsinki, Finland.
L LigthartDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
F A HagenbeekDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
M BartelsDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
L H BoglInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
L PulkkinenDepartment of Psychology, University of Jyvaskyla, Jyvaskyla, Finland.
R J RoseDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA.
D I BoomsmaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
J KaprioInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Institute for Molecular Medicine Finland · FIGGD Amsterdam · NLUniversity of Helsinki · FIVrije Universiteit Amsterdam · NLIndiana University Bloomington · USUniversity of Jyväskylä · FI

Funding

USE &ABUSE OF ALCOHOL--A BEHAVIOR-GENETICS PERSPECTIVEK05AA000145 · NIAAA · INDIANA UNIVERSITY BLOOMINGTON · PI ROSE, RICHARD JOSEPH · 1992 to 1996
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EPA EP-C-15-001NIAAA NIH HHS K05 AA000145
6 · The paper itself

Abstract

Human aggression is a complex behaviour, the biological underpinnings of which remain poorly known. To gain insights into aggression biology, we studied relationships with aggression of 11 low-molecular-weight metabolites (amino acids, ketone bodies), processed using

Indexed as

Aggression3-Hydroxybutyric AcidAdolescentAdultBayes TheoremBiomarkersChildFemaleHumansLongitudinal StudiesMaleTwinsYoung Adult3-Hydroxybutyric AcidBiomarkers

Identifiers

PMID33712630
PMCPMC7955062
OpenAlexW3134523569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.