Evidence map›Paper›PMID 33712542›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Raquel Montalbán-Loro, Glenda Lassi, Anna Lozano-Ureña, Ana Perez-Villalba, Esteban Jiménez-Villalba, Marika Charalambous, Giorgio Vallortigara, Alexa E Horner, Lisa M Saksida, Timothy J Bussey and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. TET3 protects theiScience · 2025
    Article
  5. Article
  6. Dual Role of DLK1 in GnRH Neuron Ontogeny.Stem cell reviews and reports · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Disorders of puberty and neurodevelopment: A shared etiology?Annals of the New York Academy of Sciences · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Epigenetic regulation in adult neural stem cells.Frontiers in cell and developmental biology · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Epigenetic control and genomic imprinting dynamics of the Dlk1-Dio3 domain.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 4 countries.

Raquel Montalbán-LoroERI Biotecmed-Departamento de Biología Celular, Universidad de Valencia, 46010 Valencia,Spain.ORCID 0000-0001-8048-2801
Glenda LassiGenetics and Epigenetics of Behaviour (GEB) Laboratory, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Anna Lozano-UreñaERI Biotecmed-Departamento de Biología Celular, Universidad de Valencia, 46010 Valencia,Spain.
Ana Perez-VillalbaERI Biotecmed-Departamento de Biología Celular, Universidad de Valencia, 46010 Valencia,Spain.ORCID 0000-0002-5330-2374
Esteban Jiménez-VillalbaERI Biotecmed-Departamento de Biología Celular, Universidad de Valencia, 46010 Valencia,Spain.ORCID 0000-0002-5127-9270
Marika CharalambousDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Giorgio VallortigaraCenter for Mind/Brain Sciences, University of Trento, 38068 Rovereto TN, Italy.ORCID 0000-0001-8192-9062
Alexa E HornerSynome Ltd, Babraham, Cambridge CB22 3AT, United Kingdom.ORCID 0000-0002-2632-9723
Lisa M SaksidaDepartment of Psychology, Medical Research Council and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
Timothy J BusseyDepartment of Psychology, Medical Research Council and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
José Luis TrejoDepartment of Translational Neuroscience, Cajal Institute, The Spanish National Research Council, Madrid 28002, Spain.ORCID 0000-0003-0618-5547
Valter TucciGenetics and Epigenetics of Behaviour (GEB) Laboratory, Istituto Italiano di Tecnologia, 16163 Genova, Italy.ORCID 0000-0002-3796-3826
Anne C Ferguson-SmithDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom; afsmith@gen.cam.ac.uk sacramento.rodriguez@uv.es.
Sacri R FerrónERI Biotecmed-Departamento de Biología Celular, Universidad de Valencia, 46010 Valencia,Spain; afsmith@gen.cam.ac.uk sacramento.rodriguez@uv.es.
Universitat de València · ESUniversity of Cambridge · GBWestern University · CAAstraZeneca (United Kingdom) · GBInstituto Cajal · ESItalian Institute of Technology · ITSynome (United Kingdom) · GBUniversity of Trento · IT

Funding

Medical Research Council MR/L002345/2Medical Research Council MR/R009791/1Medical Research Council MR/R022836/1Medical Research Council MR/S00002X/1Wellcome Trust 210757/Z/18/ZWellcome Trust 21757/Z/18/Z
6 · The paper itself

Abstract

Neurogenesis in the adult brain gives rise to functional neurons, which integrate into neuronal circuits and modulate neural plasticity. Sustained neurogenesis throughout life occurs in the subgranular zone (SGZ) of the dentate gyrus in the hippocampus and is hypothesized to be involved in behavioral/cognitive processes such as memory and in diseases. Genomic imprinting is of critical importance to brain development and normal behavior, and exemplifies how epigenetic states regulate genome function and gene dosage. While most genes are expressed from both alleles, imprinted genes are usually expressed from either the maternally or the paternally inherited chromosome. Here, we show that in contrast to its canonical imprinting in nonneurogenic regions,

Indexed as

Gene DosageAllelesAnimalsCalcium-Binding ProteinsCognitionHippocampusMiceNeurogenesisCalcium-Binding ProteinsDlk1 protein, mousebehaviorgene dosagegenomic imprintinghippocampusneurogenesis

Identifiers

PMID33712542
PMCPMC7980393
OpenAlexW3133907890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.