Evidence map›Paper›PMID 33712528›Full record

ArticleJournal of the American Society of Nephrology : JASN2021

Association between Longer Travel Distance for Transplant Care and Access to Kidney Transplantation and Graft Survival in the United States.

Adrian M Whelan, Kirsten L Johansen, Sandeep Brar, Charles E McCulloch, Deborah B Adey, Garrett R Roll, Barbara Grimes, Elaine Ku

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Listing at non-local transplant centers is associated with increased access to deceased donor kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adrian M WhelanDivision of Nephrology, Department of Medicine, University of California, San Francisco, California.ORCID 0000-0001-5792-6574
Kirsten L JohansenDivision of Nephrology, Department of Medicine, University of California, San Francisco, California.ORCID 0000-0001-6421-361
Sandeep BrarDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California.
Deborah B AdeyDivision of Nephrology, Department of Medicine, University of California, San Francisco, California.
Garrett R RollDivision of Transplant Surgery, Department of Surgery, University of California, San Francisco, California.
Barbara GrimesDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California.
Elaine KuDivision of Nephrology, Department of Medicine, University of California, San Francisco, California.ORCID 0000-0002-7774-2526

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Racial disparities in access to kidney transplantationR01DK115629 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI R. Adams Dudley, KIRSTEN L. JOHANSEN · 2018 to 2026
$4.5M
Prevalence and Impact of Frailty among Dialysis PatientsK24DK085153 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHANSEN, KIRSTEN L. · 2010 to 2021
$1.5M
NCATS NIH HHS UL1 TR001872NIDDK NIH HHS K24 DK085153NIDDK NIH HHS R01 DK115629
6 · The paper itself

Abstract

backgroundTransplant candidates may gain an advantage by traveling to receive care at a transplant center that may have more favorable characteristics than their local center. Factors associated with longer travel distance for transplant care and whether the excess travel distance (ETD) is associated with access to transplantation or with graft failure are unknown.

methodsThis study of adults in the United States wait-listed for kidney transplantation in 1995-2015 used ETD, defined as distance a patient traveled beyond the nearest transplant center for initial waiting list registration. We used linear regression to examine patient and center characteristics associated with ETD and Fine-Gray models to examine the association between ETD (modeled as a spline) and time to deceased or living donor transplantation or graft failure.

resultsOf 373,365 patients, 11% had an ETD≥50 miles. Traveling excess distance was more likely among patients who were of non-Black race or those whose nearest transplant center had lower annual living donor transplant volume. At an ETD of 50 miles, we observed a lower likelihood of deceased donor transplantation (subhazard ratio [SHR], 0.85; 95% confidence interval [95% CI], 0.84 to 0.87) but higher likelihood of living donor transplantation (SHR, 1.14; 95% CI, 1.12 to 1.16) compared with those who received care at their nearest center. ETD was weakly associated with higher risk of graft failure.

conclusionsPatients who travel excess distances for transplant care have better access to living donor but not deceased donor transplantation and slightly higher risk of graft failure. Traveling excess distances is not clearly associated with better outcomes, especially if living donors are unavailable.

Indexed as

Graft SurvivalKidney TransplantationTravelAdultFemaleHealth Services AccessibilityHumansKidney DiseasesMaleMiddle AgedSocioeconomic FactorsTissue and Organ ProcurementUnited StatesWaiting Listshealth policykidney transplantationorgan allocationpatient preferences

Identifiers

PMID33712528
PMCPMC8259680

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.