Evidence map›Paper›PMID 33712512›Full record

ArticleJournal of epidemiology and community health2021

Longitudinal effects of perinatal social support on maternal depression: a marginal structural modelling approach.

Ashley Hagaman, Katherine LeMasters, Paul N Zivich, Siham Sikander, Lisa M Bates, Sonia Bhalotra, Esther O Chung, Ahmed Zaidi, Joanna Maselko

Open access · greenAbstract read
In one paragraph

Article in Journal of epidemiology and community health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Ashley HagamanSocial Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA ashley.hagaman@yale.edu.ORCID 0000-0002-8016-1036
Katherine LeMastersDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Paul N ZivichDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Siham SikanderHuman Development Research Foundation, Islamabad, Pakistan.
Lisa M BatesDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Sonia BhalotraDepartment of Economics, University of Warwick, UK, Coventry, Warwickshire, UK.
Esther O ChungDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ahmed ZaidiHuman Development Research Foundation, Islamabad, Pakistan.
Joanna MaselkoDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · USHuman Development Research Foundation · PKColumbia University · USUniversity of Warwick · GBYale University · US

Funding

POPULATION STUDIEST32HD007168 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 1985 to 2026
$13.8M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Impact of Perinatal Depression treatment on child developmental outcomesR01HD075875 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MASELKO, JOANNA · 2014 to 2024
$5.2M
From Biological to Social Processes: Interdisciplinary Training in Life Course ResearchT32HD091058 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT A HUMMER, Amanda L Thompson · 2017 to 2026
$4.3M
South Asian Hub for Advocacy, Research & Education on Mental Health (SHARE)U19MH095687 · NIMH · LONDON SCH/HYGIENE & TROPICAL MEDICINE · PI PATEL, VIKRAM H, RAHMAN, ATIF · 2011 to 2015
$2.9M
Opportunities for suicide prevention integration into task-shifted mental health interventions in low-resourced contextsK01MH125142 · NIMH · YALE UNIVERSITY · PI HAGAMAN, ASHLEY K · 2021 to 2025
$964k
NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD075875NICHD NIH HHS R24 HD050924NICHD NIH HHS T32 HD007168NICHD NIH HHS T32 HD091058NIMH NIH HHS K01 MH125142NIMH NIH HHS U19 MH095687
6 · The paper itself

Abstract

backgroundDepression in the perinatal period, during pregnancy or within 1 year of childbirth, imposes a high burden on women with rippling effects through her and her child's life course. Social support may be an important protective factor, but the complex bidirectional relationship with depression, alongside a paucity of longitudinal explorations, leaves much unknown about critical windows of social support exposure across the perinatal period and causal impacts on future depressive episodes.

methodsThis study leverages marginal structural models to evaluate associations between longitudinal patterns of perinatal social support and subsequent maternal depression at 6 and 12 months postpartum. In a cohort of women in rural Pakistan (n=780), recruited in the third trimester of pregnancy and followed up at 3, 6 and 12 months postpartum, we assessed social support using two well-validated measures: the Multidimensional Scale of Perceived Social Support (MSPSS) and the Maternal Social Support Index (MSSI). Major depressive disorder was assessed with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (DSM IV).

resultsHigh and sustained scores on the MSPSS through the perinatal period were associated with a decreased risk of depression at 12 months postpartum (0.35, 95% CI: 0.19 to 0.63). Evidence suggests the recency of support also matters, but estimates are imprecise. We did not find evidence of a protective effect for support based on the MSSI.

conclusionsThis study highlights the protective effect of sustained social support, particularly emotional support, on perinatal depression. Interventions targeting, leveraging and maintaining this type of support may be particularly important for reducing postpartum depression.

Indexed as

Depression, PostpartumMajor Depressive DisorderChildDepressionFemaleHumansModels, StructuralPostpartum PeriodPregnancySocial Supportdepressiondeveloping countrymaternal healthpsychosocial factors

Identifiers

PMID33712512
PMCPMC8434957
OpenAlexW3134058866

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.