ArticleScience advances2021
Atoh7-independent specification of retinal ganglion cell identity.
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Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
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Who cites it
44 citing papers in PubMed, 64 citations in OpenAlex.
- The long noncoding RNA Peanut (Gm11454) biases progenitors towards neurogenesis and rod photoreceptor differentiation during postnatal retinal development.Developmental biology · 2026Article
- Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina.Current biology : CB · 2026Article
- Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids.Cell reports · 2026Article
- Technological advances in axonal regeneration and structural plasticity: optogenetics, single-cell omics, and tissue clearing.Frontiers in cellular neuroscience · 2026Review
- Active DNA demethylation upstream of rod-photoreceptor fate determination is required for retinal development.PLoS biology · 2025Article
- Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains.Nature communications · 2025Article
- Ganoderma lucidum polysaccharide attenuates retinal ischemia-reperfusion injury by regulating microglial M1/M2 polarization, suppressing neuroinflammation and inhibiting JAK2/STAT3 pathway.Biochemistry and biophysics reports · 2025Article
- Experimental Framework for Assessing Mouse Retinal Regeneration Through Single-Cell RNA-Sequencing.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Blind But Alive - Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish.Investigative ophthalmology & visual science · 2024Article
- New pathways to neurogenesis: Insights from injury-induced retinal regeneration.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024Review
- Retinal neurons establish mosaic patterning by excluding homotypic somata from their dendritic territories.Cell reports · 2024Article
- Article
- A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis.Cell reports · 2024Article
- Article
- Sstr2 Defines the Cone Differentiation-Competent Late-Stage Retinal Progenitor Cells in the Developing Mouse Retina.Stem cells translational medicine · 2024Article
- Therapeutic strategies for glaucoma and optic neuropathies.Molecular aspects of medicine · 2023Review
- Retinal neurons establish mosaic patterning by excluding homotypic somata from their dendritic territory.bioRxiv : the preprint server for biology · 2023Article
- Molecular mechanisms controlling vertebrate retinal patterning, neurogenesis, and cell fate specification.Trends in genetics : TIG · 2023Review
- Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium.Molecular neurodegeneration · 2023Review
- Establishing Functional Retina in a Dish: Progress and Promises of Induced Pluripotent Stem Cell-Based Retinal Neuron Differentiation.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
18 authors at 7 institutions in 3 countries.
Justin Brodie-KommitDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-3336-7813
Brian S ClarkJohn F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-7291-2055
Qing ShiDepartment of Biology, University of Maryland, College Park, MD, USA.
Fion ShiauJohn F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-0848-6562
Dong Won KimDepartment of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8624-0168
Jennifer LangelNational Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, MD, USA.
Catherine SheelyDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-6368-177X
Philip A RuzyckiJohn F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-3520-6407
Michel FriesCellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada.
Awais JavedCellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada.ORCID 0000-0002-2686-8006
Michel CayouetteCellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada.ORCID 0000-0003-4655-9048
Tiffany SchmidtDepartment of Neurobiology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-4791-6775
Tudor BadeaNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3086-6713
Tom GlaserDepartment of Cell Biology and Human Anatomy, University of California, Davis School of Medicine, Davis, CA, USA.ORCID 0000-0003-1000-2301
Haiqing ZhaoDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Joshua SingerDepartment of Biology, University of Maryland, College Park, MD, USA.ORCID 0000-0002-0561-2247
Seth BlackshawDepartment of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. samer.hattar@nih.gov sblack@jhmi.edu.ORCID 0000-0002-1338-8476
Samer HattarNational Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, MD, USA. samer.hattar@nih.gov sblack@jhmi.edu.ORCID 0000-0002-3124-9525
Johns Hopkins University · USMontreal Clinical Research Institute · CANational Institutes of Health · USUniversity of Maryland, College Park · USNorthwestern University · USUniversity of California, Davis · USWashington University in St. Louis · US
Funding
Section on Light and Circadian RhythmsZIAMH002964 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HATTAR, SAMER · 2017 to 2025
$24.1MCELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4MRetinal Circuit Development & GeneticsZIAEY000504 · NEI · NATIONAL EYE INSTITUTE · PI BADEA, TUDOR · 2011 to 2021
$15.6MRegulation of the intrinsic melanopsin-based light response in ipRGCsR01EY027202 · NEI · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI RONALD Lane BROWN, Joseph Leffler · 2017 to 2026
$5.3MRole of mammalian retinal photoreceptors in non-image-forming visual functionsR01GM076430 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ZHAO, HAIQING · 2005 to 2018
$4.8MTranscriptional regulation of retinal cell differentiation and functionR01EY020560 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2011 to 2021
$4.4MGenetic Basis of Congenital AnophthalmiaR01EY019497 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GLASER, THOMAS M. · 2009 to 2020
$3.3MCRCNS: Biophysical properties of parallel neural circuits serving night visionR01EY021372 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI DEMB, JONATHAN B, SINGER, JOSHUA H · 2010 to 2016
$2.1MIdentification of gene regulatory networks that control proliferative and neurogenic competence in mammalian Müller gliaR01EY031685 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2020 to 2023
$2.0MThe Role of CFAP69 in OlfactionR01DC016065 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI ZHAO, HAIQING · 2018 to 2022
$2.0MIdentification of the molecular mechanisms mediating intrinsic control of retinal progenitor competenceR00EY027844 · NEI · WASHINGTON UNIVERSITY · PI CLARK, BRIAN S · 2019 to 2021
$739kDevelopmental origins of intrinsically photosensitive retinal ganglion cellsF32EY022543 · NEI · JOHNS HOPKINS UNIVERSITY · PI SCHMIDT, TIFFANY M. · 2012 to 2014
$124kNEI NIH HHS F32 EY022543NEI NIH HHS R00 EY027844NEI NIH HHS R01 EY019497NEI NIH HHS R01 EY020560NEI NIH HHS R01 EY021372NEI NIH HHS R01 EY027202NEI NIH HHS R01 EY031685NIDCD NIH HHS R01 DC016065NIGMS NIH HHS R01 GM076430NIGMS NIH HHS T32 GM007231
Abstract
Retinal ganglion cells (RGCs) relay visual information from the eye to the brain. RGCs are the first cell type generated during retinal neurogenesis. Loss of function of the transcription factor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.