Evidence map›Paper›PMID 33711582›Full record

ReviewOral oncology2021

The contribution of artificial intelligence to reducing the diagnostic delay in oral cancer.

Betul Ilhan, Pelin Guneri, Petra Wilder-Smith

Abstract readReview
In one paragraph

Review in Oral oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Artificial Intelligence in Dentistry: A Descriptive Review.Bioengineering (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Betul IlhanEge University, Faculty of Dentistry, Department of Oral & Maxillofacial Radiology, Bornova, Izmir, Turkey. Electronic address: ilhanbetul@yahoo.com.
Pelin GuneriEge University, Faculty of Dentistry, Department of Oral & Maxillofacial Radiology, Bornova, Izmir, Turkey.
Petra Wilder-SmithBeckman Laser Institute, University of California, Irvine, CA, USA.

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI BOTVINICK, ELLIOT LAWRENCE · 2012 to 2017
$7.0M
Low-cost Mobile Oral Cancer Screening for Low Resource SettingUH2EB022623 · NIBIB · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2016 to 2017
$996k
A Low-Cost Simple Oral Cancer Screening Device for Low-Resource SettingsR03EB014852 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI WILDER-SMITH, PETRA E · 2012 to 2015
$249k
NCI NIH HHS P30 CA062203NIBIB NIH HHS P41 EB015890NIBIB NIH HHS R03 EB014852NIBIB NIH HHS UH2 EB022623
6 · The paper itself

Abstract

Oral cancer (OC) is the sixth most commonly reported malignant disease globally, with high rates of disease-related morbidity and mortality due to advanced loco-regional stage at diagnosis. Early detection and prompt treatment offer the best outcomes to patients, yet the majority of OC lesions are detected at late stages with 45% survival rate for 2 years. The primary cause of poor OC outcomes is unavailable or ineffective screening and surveillance at the local point-of-care level, leading to delays in specialist referral and subsequent treatment. Lack of adequate awareness of OC among the public and professionals, and barriers to accessing health care services in a timely manner also contribute to delayed diagnosis. As image analysis and diagnostic technologies are evolving, various artificial intelligence (AI) approaches, specific algorithms and predictive models are beginning to have a considerable impact in improving diagnostic accuracy for OC. AI based technologies combined with intraoral photographic images or optical imaging methods are under investigation for automated detection and classification of OC. These new methods and technologies have great potential to improve outcomes, especially in low-resource settings. Such approaches can be used to predict oral cancer risk as an adjunct to population screening by providing real-time risk assessment. The objective of this study is to (1) provide an overview of components of delayed OC diagnosis and (2) evaluate novel AI based approaches with respect to their utility and implications for improving oral cancer detection.

Indexed as

Delayed DiagnosisMouth NeoplasmsAlgorithmsArtificial IntelligenceHumansImage Processing, Computer-AssistedArtificial intelligenceDiagnostic delayEarly detectionOral cancerOral cancer diagnosis

Identifiers

PMID33711582
PMCPMC8144066

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.