Evidence map›Paper›PMID 33711538›Full record

ArticleJournal of biomedical informatics2021

Efficient verification for outsourced genome-wide association studies.

Xinyue Wang, Xiaoqian Jiang, Jaideep Vaidya

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Descriptor:IEEE data descriptions · 2024
    Article
  3. Article
  4. Efficient Federated Kinship Relationship Identification.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023
    Article
  5. Privacy-Preserving and Efficient Verification of the Outcome in Genome-Wide Association Studies.Proceedings on Privacy Enhancing Technologies. Privacy Enhancing Technologies Symposium · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinyue WangRutgers University, Newark, NJ, USA.
Xiaoqian JiangUniversity of Texas Health Science Center at Houston, TX, USA.
Jaideep VaidyaRutgers University, Newark, NJ, USA. Electronic address: jsvaidya@business.rutgers.edu.

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Supplement for high performance compute clustersR35GM134927 · NIGMS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI VAIDYA, JAIDEEP · 2020 to 2024
$2.1M
Secure and PrivAte Collaborative EnvironmentS (SPACES) for biomedical analyticsR01GM118574 · NIGMS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI VAIDYA, JAIDEEP · 2017 to 2019
$1.1M
SHARE: Statistical Health Information Release with Differential PrivacyR01GM114612 · NIGMS · EMORY UNIVERSITY · PI XIONG, LI · 2015 to 2017
$1.0M
NCATS NIH HHS U01 TR002062NIGMS NIH HHS R01 GM114612NIGMS NIH HHS R01 GM118574NIGMS NIH HHS R35 GM134927
6 · The paper itself

Abstract

With cloud computing is being widely adopted in conducting genome-wide association studies (GWAS), how to verify the integrity of outsourced GWAS computation remains to be accomplished. Here, we propose two novel algorithms to generate synthetic SNPs that are indistinguishable from real SNPs. The first method creates synthetic SNPs based on the phenotype vector, while the second approach creates synthetic SNPs based on real SNPs that are most similar to the phenotype vector. The time complexity of the first approach and the second approach is Om and Omlogn

Indexed as

Cloud ComputingGenome-Wide Association StudyAlgorithmsHumansPhenotypePolymorphism, Single NucleotideComputational integrityEfficient verificationGenome wide association study

Identifiers

PMID33711538
PMCPMC8131235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.