ArticleOrthodontics & craniofacial research2021
3D morphometric quantification of maxillae and defects for patients with unilateral cleft palate via deep learning-based CBCT image auto-segmentation.
Article in Orthodontics & craniofacial research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Standardization and Validation of Digital Volumetric Measurement Methods for Alveolar Cleft Defects Using 3D Imaging.Dentistry journal · 2026Article
- Artificial intelligence applications in the diagnosis and management of cleft lip and palate: An updated review.Journal of dental sciences · 2026Review
- Applications of artificial intelligence in diagnosis and treatment planning of orthodontics: a narrative review.The Saudi dental journal · 2025Review
- Development of Artificial Intelligence-Supported Automatic Three-Dimensional Surface Cephalometry.Orthodontics & craniofacial research · 2025Article
- Artificial Intelligence Applications in Pediatric Craniofacial Surgery.Diagnostics (Basel, Switzerland) · 2025Review
- Harnessing the Power of Artificial Intelligence in Cleft Lip and Palate: An In-Depth Analysis from Diagnosis to Treatment, a Comprehensive Review.Children (Basel, Switzerland) · 2024Review
- Application of Artificial Intelligence in Clinical Dentistry, a Comprehensive Review of Literature.Journal of dentistry (Shiraz, Iran) · 2023Review
- Performance of artificial intelligence using cone-beam computed tomography for segmentation of oral and maxillofacial structures: A systematic review and meta-analysis.Journal of clinical and experimental dentistry · 2023Review
- Interpretable artificial intelligence for classification of alveolar bone defect in patients with cleft lip and palate.Scientific reports · 2023Article
- Deep Learning in Diagnosis of Dental Anomalies and Diseases: A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
- A Scoping Review of Artificial Intelligence Research in Rhinology.American journal of rhinology & allergy · 2023Article
- Unilateral Cleft Lip and Palate Has Asymmetry of Bony Orbits: A Retrospective Study.Journal of personalized medicine · 2023Article
- Deep Learning-Based Medical Images Segmentation of Musculoskeletal Anatomical Structures: A Survey of Bottlenecks and Strategies.Bioengineering (Basel, Switzerland) · 2023Review
- Machine learning in 3D auto-filling alveolar cleft of CT images to assess the influence of alveolar bone grafting on the development of maxilla.BMC oral health · 2023Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 3 countries.
Funding
Abstract
objectiveThis study aimed to quantify the 3D asymmetry of the maxilla in patients with unilateral cleft lip and palate (UCP) and investigate the defect factors responsible for the variability of the maxilla on the cleft side using a deep-learning-based CBCT image segmentation protocol. SETTING AND SAMPLE POPULATION: Cone beam computed tomography (CBCT) images of 60 patients with UCP were acquired. The samples in this study consisted of 39 males and 21 females, with a mean age of 11.52 years (SD = 3.27 years; range of 8-18 years). MATERIALS AND
methodsThe deep-learning-based protocol was used to segment the maxilla and defect initially, followed by manual refinement. Paired t-tests were performed to characterize the maxillary asymmetry. A multiple linear regression was carried out to investigate the relationship between the defect parameters and those of the cleft side of the maxilla.
resultsThe cleft side of the maxilla demonstrated a significant decrease in maxillary volume and length as well as alveolar length, anterior width, posterior width, anterior height and posterior height. A significant increase in maxillary anterior width was demonstrated on the cleft side of the maxilla. There was a close relationship between the defect parameters and those of the cleft side of the maxilla.
conclusionsBased on the 3D volumetric segmentations, significant hypoplasia of the maxilla on the cleft side existed in the pyriform aperture and alveolar crest area near the defect. The defect structures appeared to contribute to the variability of the maxilla on the cleft side.
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