Trial reportThe British journal of surgery2021
Chronic pain after open inguinal hernia repair: expertise-based randomized clinical trial of heavyweight or lightweight mesh.
Trial report in The British journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00451893 (An Expertise-based Multicentre Randomized Controlled Trial Comparing a Heavy-weight and a Light-weight Mesh in the Operation of Inguinal Hernia), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Expertise-based Multicentre Randomized Controlled Trial Comparing a Heavy-weight and a Light-weight Mesh in the Operation of Inguinal Hernia
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of short- and long-term efficacy and economic indicators between transabdominal preperitoneal and open tension-free repair for inguinal hernia in adults: a meta-analysis of randomized controlled trials.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- One-year outcome after open inguinal hernia repair with self-fixated mesh: a randomized controlled trial.Langenbeck's archives of surgery · 2023Trial
- Preoperative predictors of chronic pain after laparoendoscopic groin hernia repair: A Swedish Hernia Registry study.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Is mesh pore size in polypropylene meshes associated with the outcome in Lichtenstein inguinal hernia repair: a registry-based analysis of 22,141 patients.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Lichtenstein technique for inguinal hernia repair: ten recommendations to optimize surgical outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- A novel electrospun polylactic acid silkworm fibroin mesh for abdominal wall hernia repair.Materials today. Bio · 2024Article
- The Lichtenstein technique is being used adequately in inguinal hernia repair: national analysis and review of the surgical technique.Revista do Colegio Brasileiro de Cirurgioes · 2023Review
- Definition of Mesh Weight and Pore Size in Groin Hernia Repair: A Systematic Scoping Review of Randomised Controlled Trials.Journal of abdominal wall surgery : JAWS · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a shortage of high-quality studies regarding choice of mesh in open anterior inguinal hernia repair in relation to long-term chronic pain. The authors hypothesized that heavyweight compared with lightweight mesh causes increased postoperative pain.
methodsAn RCT was undertaken between 2007 and 2009 at two sites in Sweden. Men aged 25 years or older with an inguinal hernia evaluated in the outpatient clinic were randomized in an unblinded fashion to heavyweight or lightweight mesh for open anterior inguinal hernia repair. Data on pain affecting daily activities, as measured by the Short-Form Inguinal Pain Questionnaire 9-12 years after surgery, were collected as the primary outcome. Differences between groups were evaluated by generalized odds and numbers needed to treat.
resultsA total of 412 patients were randomized; 363 were analysed with 320 questionnaires sent out. A total of 271 questionnaires (84.7 per cent) were returned; of these, 121 and 150 patients were in the heavyweight and lightweight mesh groups respectively. Pain affecting daily activities was more pronounced in patients randomized to heavyweight versus lightweight mesh (generalized odds 1.33, 95 per cent c.i. 1.10 to 1.61). This translated into a number needed to treat of 7.06 (95 per cent c.i. 4.28 to 21.44). Two reoperations for recurrence were noted in the heavyweight mesh group, and one in the lightweight mesh group.
conclusionA large-pore lightweight mesh causes significantly less pain affecting daily activities a decade after open anterior inguinal hernia repair. Registration number: NCT00451893 (http://www.clinicaltrials.gov).
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