Evidence map›Paper›PMID 33710947›Full record

ArticleWomen's health (London, England)

Intravenous thrombolysis for stroke in pregnancy should be administered if the benefit outweighs the risk: A case report and recommended diagnostic workup.

Marek Bojda, Andrea Cimprichová, Bibiana Vavríková, Alena Filipková, Zuzana Gdovinová

Open access · goldAbstract readCase Reports
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marek BojdaDepartment of Neurology, Faculty Hospital Trenčín, Trencin, Slovakia.
Andrea CimprichováDepartment of Neurology, Faculty Hospital Trenčín, Trencin, Slovakia.
Bibiana VavríkováDepartment of Neurology, Faculty Hospital Trenčín, Trencin, Slovakia.
Alena FilipkováDepartment of Neurology, Faculty Hospital Trenčín, Trencin, Slovakia.
Zuzana GdovinováDepartment of Neurology, Faculty of Medicine, P.J. Šafarik University and University Hospital L. Pasteur, Košice, Slovakia.ORCID 0000-0002-7396-5052
Vysoká škola manažmentu, City University of Seattle · SKUniversity of Pavol Jozef Šafárik · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is an ongoing debate about the use of recombinant tissue plasminogen activator in acute stroke during pregnancy. The aim of our case report is to present that even in a small stroke centre intravenous thrombolysis can be used on a pregnant woman if the benefit outweighs the risk and to summarize the diagnostic workup in a pregnant woman with stroke. CASE REPORT: Our case describes a 31-year-old woman presenting in her third trimester with a sudden onset of slurred speech, severe right hemiparesis, facial nerve central palsy, eyes deviation to the left, right side hemianopia, hemisensory loss, psychomotor agitation and pain in the right lower limb. She was successfully treated with recombinant tissue plasminogen activator with almost complete recovery (NIHSS 1 after 10 days), and 23 days after intravenous thrombolysis, she delivered in the 37th week a healthy male infant. The first documented successful outcome from thrombolysis for this condition in Slovakia supports the notion of giving intravenous recombinant tissue plasminogen activator to pregnant patients with disabling ischaemic stroke who meet the criteria for thrombolysis. DISCUSSION: At the end of case study, a recommended diagnostic workup for acute treatment of stroke in pregnant women is presented.

Indexed as

Brain IschemiaPregnancy Complications, CardiovascularStrokeAdultFemaleHumansMalePregnancyThrombolytic TherapyTissue Plasminogen ActivatorTreatment OutcomeTissue Plasminogen Activatorintravenous thrombolysispregnancystroke

Identifiers

PMID33710947
PMCPMC7958154
OpenAlexW3135351322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.