Evidence map›Paper›PMID 33710659›Full record

Trial reportMovement disorders : official journal of the Movement Disorder Society2021

Innovating Parkinson's Care: A Randomized Controlled Trial of Telemedicine Depression Treatment.

Roseanne D Dobkin, Sarah L Mann, Daniel Weintraub, Kailyn M Rodriguez, Rachael B Miller, Lauren St Hill, Arlene King, Michael A Gara, Alejandro Interian

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Movement disorders : official journal of the Movement Disorder Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02475954 (Telehealth Cognitive-Behavioral Therapy for Depression in Parkinson's Disease), which is not on this map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02475954 nacompletednot on this map

Telehealth Cognitive-Behavioral Therapy for Depression in Parkinson's Disease

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2016 to 2019Enrolled174ConditionsDepression, Parkinson's DiseaseArmsTH-CBT, Standard Care
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  5. Efficacy of cognitive behavioral therapy for anxiety and depression in Parkinson's disease patients: an updated systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Perspective: Depression in Persons with Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Review
  10. Bridging the Rural Mental Health Gap: Telehealth Delivery of Specialized CBT and MBCT for Veterans With Parkinson's Disease.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
    Article
  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Roseanne D DobkinRutgers-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Sarah L MannVA New Jersey Health Care System, Lyons, New Jersey, USA.
Daniel WeintraubPerelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-0633-7168
Kailyn M RodriguezVA New Jersey Health Care System, Lyons, New Jersey, USA.
Rachael B MillerVA New Jersey Health Care System, Lyons, New Jersey, USA.
Lauren St HillVA New Jersey Health Care System, Lyons, New Jersey, USA.
Arlene KingVA New Jersey Health Care System, Lyons, New Jersey, USA.
Michael A GaraRutgers-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Alejandro InterianVA New Jersey Health Care System, Lyons, New Jersey, USA.
VA New Jersey Health Care System · USRutgers, The State University of New Jersey · USVeterans Health Administration · US

Funding

HSRD VA I01 HX001714
6 · The paper itself

Abstract

backgroundFor several decades, a myriad of factors have contributed to the inadequate diagnosis and management of depression in Parkinson's disease (PD), leaving up to 60% of significantly symptomatic patients untreated. Poor access to evidence-based neuropsychiatric care is one major barrier to achieving optimal Parkinson's outcomes.

objectiveThe goal of this study was to compare the efficacy of individual Parkinson's-informed, video-to-home cognitive-behavioral therapy (experimental group), to clinic-based treatment as usual (control group), for depression in PD.

methodNinety United States military veterans with clinical diagnoses of both depression and PD were computer-randomized (1:1) to either the experimental or control group; randomization was stratified by baseline antidepressant use and blind to all other baseline data. The acute treatment period spanned 10 weeks and was followed by a 6-month extension phase. The Hamilton Depression Rating Scale was the a priori primary outcome. Depression treatment response was defined as a score ≤2 on the Clinical Global Impression Improvement Scale. All statistical analyses were intent to treat.

resultsVideo-to-home cognitive-behavioral therapy outperformed clinic-based treatment as usual across three separate depression measures (P < 0.001). Effects were observed at the end of acute treatment and maintained through 6-month follow-up. Number needed to treat (based on treatment response classification) was 2.5 with an absolute risk reduction of 40%.

conclusionVideo-to-home cognitive-behavioral therapy may be an effective intervention to bypass access barriers to specialized, evidence-based depression care in PD and to address the unmet neuropsychiatric treatment needs of the Parkinson's community. © 2021 International Parkinson and Movement Disorder Society.

Indexed as

Cognitive Behavioral TherapyParkinson DiseaseTelemedicineDepressionHumansTreatment Outcomedepressionevidence-based careParkinson's diseasetelemedicine

Identifiers

PMID33710659
PMCPMC11822725
OpenAlexW3134712891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.