Evidence map›Paper›PMID 33710502›Full record

ArticleClinical journal of gastroenterology2021

Delay of endoscopic submucosal dissection-induced gastric ulcer healing by methotrexate.

Shu Kiyotoki, Jun Nishikawa, Jutaro Miyamoto, Koji Tanigawa, Seiji Tsuchida, Ryo Kawasato, Takao Nakashima, Takakazu Furutani, Hirokazu Ozawa, Mitsuru Yasunaga and 1 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shu KiyotokiDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan. shu2026eb@hi.enjoy.ne.jp.ORCID http://orcid.org/0000-0002-6417-4638
Jun NishikawaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube, 755-8505, Japan.
Jutaro MiyamotoDepartment of Oral and Maxillofacial Surgery, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Koji TanigawaDepartment of Gastroenterology, Hikari Municipal Hikari General Hospital, 6-1 Hikarigaoka, Hikari, 743-8561, Japan.
Seiji TsuchidaDepartment of Orthopedics, Hikari Municipal Hikari General Hospital, 6-1 Hikarigaoka, Hikari, 743-8561, Japan.
Ryo KawasatoDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Takao NakashimaDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Takakazu FurutaniDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Hirokazu OzawaDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Mitsuru YasunagaDepartment of Gastroenterology, Shuto General Hospital, Kogaisaku 1000-1, Yanai, 742-0032, Japan.
Isao SakaidaDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube, 755-8505, Japan.
Shuto General Hospital · JPHikari Giken (Japan) · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of methotrexate (MTX) delaying the healing of an endoscopic submucosal dissection (ESD)-induced gastric ulcer. The patient, who had been taking MTX for rheumatoid arthritis, underwent ESD for early gastric carcinoma. Despite taking vonoprazan after ESD, abdominal pain and anorexia continued, and the gastric ulcer did not heal after the ESD. After discontinuing MTX, the patient's symptoms improved and the ulcer healed. Patients taking MTX require careful follow-up after ESD, considering that ulcers can be difficult to heal. Discontinuation of MTX should be considered if delayed healing of an ulcer is observed.

Indexed as

Endoscopic Mucosal ResectionStomach NeoplasmsStomach UlcerGastric MucosaHumansMethotrexateProton Pump InhibitorsUlcerMethotrexateProton Pump InhibitorsDelayed ulcer healingEndoscopic submucosal dissectionGastric carcinomaGastric ulcerMethotrexate

Identifiers

PMID33710502
OpenAlexW3135023619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.