ArticleJournal of medical entomology2021
Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus).
Article in Journal of medical entomology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
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Who cites it
27 citing papers in PubMed.
- Sialic acids are a barrier to the entry of non-influenza orthomyxoviruses.PLoS pathogens · 2026Article
- Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026Review
- It takes a village: Community science informs tick encounter, pathogen, and exposure risk in North Carolina, USA.PloS one · 2026Article
- Co-feeding transmission of Heartland virus between the North American tick, Amblyomma americanum (Acari: Ixodidae), and the invasive East Asian tick, Haemaphysalis longicornis (Acari: Ixodidae).Journal of medical entomology · 2025Article
- A novel accessory gene product of tick-borne Dhori-Orthomyxovirus, encoded by overlooked spliced transcripts of RNA segment 6.Journal of virology · 2025Article
- Environmental correlates and fine-scale distribution of Amblyomma americanum, Ehrlichia spp., and Rickettsia amblyommatis at a single site in south-central Virginia.Parasites & vectors · 2025Article
- Surveillance for Serological Evidence of Bourbon and Heartland Virus Infection in White-Tailed Deer and Feral Swine in Texas.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2025Article
- Public health significance of the white-tailed deer (Odocoileus virginianus) and its role in the eco-epidemiology of tick- and mosquito-borne diseases in North America.Parasites & vectors · 2025Review
- Ticks and tick-borne diseases in the northern hemisphere affecting humans.Frontiers in microbiology · 2025Review
- Tick-borne viruses: Epidemiology, pathogenesis, and animal models.One health (Amsterdam, Netherlands) · 2024Review
- Ecological relationships ofParasitology · 2024Article
- Widespread Circulation of Tick-Borne Viruses in Virginia-Evidence of Exposure to Heartland, Bourbon, and Powassan Viruses in Wildlife and Livestock.Microorganisms · 2024Article
- Diversification of Bourbon Virus in New York State.Microorganisms · 2023Article
- Zebrafish-based platform for emerging bio-contaminants and virus inactivation research.The Science of the total environment · 2023Review
- Bourbon Virus Transmission, New York, USA.Emerging infectious diseases · 2023Article
- Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States.Emerging infectious diseases · 2023Review
- Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA.Ticks and tick-borne diseases · 2023Article
- Tick Species Composition, Collection Rates, and Phenology Provide Insights into Tick-Borne Disease Ecology in Virginia.Journal of medical entomology · 2022Article
- Tick species infesting humans in the United States.Ticks and tick-borne diseases · 2022Review
- Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA.mSphere · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Following the recent discovery of Bourbon virus (BRBV) as a human pathogen, and the isolation of the virus from Amblyomma americanum (L.) collected near the location of a fatal human case, we undertook a series of experiments to assess the laboratory vector competence of this tick species for BRBV. Larval ticks were infected using an immersion technique, and transstadial transmission of virus to the nymphal and then to the adult stages was demonstrated. Transstadially infected nymphs transmitted virus to adult ticks at very high rates during cofeeding, indicating the presence of infectious virus in the saliva of engorging ticks. Vertical transmission by transstadially infected females to their progeny occurred, but at a low rate. Rabbits fed on by infected ticks of all active life stages developed high titers of antibody to the virus, demonstrating host exposure to BRBV antigens/live virus during tick blood feeding. These results demonstrate that A. americanum is a competent vector of BRBV and indicate that cofeeding could be critical for enzootic maintenance.
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