ArticleThe Journal of hand surgery, European volume2021
Defining abnormal cold sensitivity using the Cold Intolerance Symptom Severity questionnaire: a population study.
Article in The Journal of hand surgery, European volume, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06915662 (Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap), which is not on this map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap: A Prospective Trial for Safety and Efficacy
Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- A new biomarker for screening Hiesho (cold hypersensitivity) in young females through measurement of the foot temperature-recovery rate after a cooling test.BMC women's health · 2025Article
- High Prevalence of Cold Intolerance in Rheumatoid Arthritis: A Case-Control Study.Clinical case reports · 2025Article
- Patient-reported significant disability after major traumatic upper extremity amputation.The Journal of hand surgery, European volume · 2024Article
- A Prospective Follow-up Study of Fingertip Amputation Treatment With Semi-occlusive Dressing.Plastic and reconstructive surgery. Global open · 2023Article
- Cold sensitivity, functional disability and predicting factors after a repaired digital nerve injury.Scientific reports · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cold sensitivity, a common and disabling sequela of hand injury, can be assessed using the Cold Intolerance Symptom Severity (CISS) questionnaire, rating symptoms on a scale from 4 to 100. The primary objective of this study was to define a clinical cut-off for abnormal cold sensitivity based on the CISS score in a healthy working-age population. The secondary objective was to investigate how age, gender and previous injuries and diseases influence CISS scoring. In this study, 1239 out of 1582 selected healthy subjects of working age living in northern Sweden completed the questionnaire, yielding a response rate of 78%. The 95th percentile for the CISS score was 49.5 for men and 53.0 for women. The effects of age, gender and previous injuries and diseases were minor and not considered clinically relevant. The results support that a CISS score above 50 should be considered as abnormal cold sensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.