Evidence map›Paper›PMID 33709335›Full record

ReviewMycopathologia2021

Respiratory Mycoses in COPD and Bronchiectasis.

Pei Yee Tiew, Micheál Mac Aogáin, Soo Kai Ter, Stefano Aliberti, James D Chalmers, Sanjay H Chotirmall

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Fungal lung disease.The European respiratory journal · 2024
    Review
  8. Biomarkers in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  9. The Precision Medicine Era of Bronchiectasis.American journal of respiratory and critical care medicine · 2024
    Article
  10. Review
  11. Review
  12. Sensitisation to recombinantThe European respiratory journal · 2023
    Article
  13. Article
  14. ClinicalJournal of fungi (Basel, Switzerland) · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Pei Yee TiewLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Nanyang, 308232, Singapore.
Micheál Mac AogáinBiochemical Genetics Laboratory, Department of Biochemistry, St. James's Hospital, Dublin, Ireland.
Soo Kai TerLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Nanyang, 308232, Singapore.
Stefano AlibertiRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
James D ChalmersSchool of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland.
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Nanyang, 308232, Singapore. schotirmall@ntu.edu.sg.ORCID http://orcid.org/0000-0003-0417-7607
Nanyang Technological University · SGTrinity College Dublin · IEUniversity of Dundee · GBUniversity of Milan · IT

Funding

British Lung Foundation British Lung Foundation through the GSK/British Lung Foundation Chair of Respiratory ResearchNational Medical Research Council Singapore MOH-000141National Medical Research Council Singapore NMRC/Fellowship/0049/2017NTU Integrated Medical, Biological and Environmental Life Sciences (NIMBELS) NIM/03/2018
6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) and bronchiectasis represent chronic airway diseases associated with significant morbidity and mortality. Bacteria and viruses are commonly implicated in acute exacerbations; however the significance of fungi in these airways remains poorly defined. While COPD and bronchiectasis remain recognized risk factors for the occurrence of Aspergillus-associated disease including chronic and invasive aspergillosis, underlying mechanisms that lead to the progression from colonization to invasive disease remain uncertain. Nonetheless, advances in molecular technologies have improved our detection, identification and understanding of resident fungi characterizing these airways. Mycobiome sequencing has revealed the complex varied and myriad profile of airway fungi in COPD and bronchiectasis, including their association with disease presentation, progression, and mortality. In this review, we outline the emerging evidence for the clinical importance of fungi in COPD and bronchiectasis, available diagnostic modalities, mycobiome sequencing approaches and association with clinical outcomes.

Indexed as

BronchiectasisMycosesPulmonary AspergillosisPulmonary Disease, Chronic ObstructiveAspergillusHumansAspergillusFungiITS sequencingMycobiomeRespiratory mycoses

Identifiers

PMID33709335
OpenAlexW3133629283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.