Evidence map›Paper›PMID 33709258›Full record

ArticleEuropean child & adolescent psychiatry2022

Influence of motivational placebo-related factors on the effects of exercise treatment in depressive adolescents.

Heidrun Lioba Wunram, Stefanie Hamacher, Max Oberste, Susanne Neufang, Luisa Belke, Franziska Jänicke, Christine Graf, Eckhard Schönau, Stephan Bender, Oliver Fricke

Open access · hybridAbstract read
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In one paragraph

Article in European child & adolescent psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Heidrun Lioba WunramDepartment of Child and Adolescent Psychiatry Psychosomatic and Psychotherapy, University Hospital of Cologne, Cologne, Germany. heidrun-lioba.wunram@uk-koeln.de.ORCID http://orcid.org/0000-0002-9140-6000
Stefanie HamacherDepartment of Medical Statistics, Informatics and Epidemiology (IMSIE), University of Cologne, Cologne, Germany.
Max ObersteDepartment of Medical Statistics, Informatics and Epidemiology (IMSIE), University of Cologne, Cologne, Germany.
Susanne NeufangDepartment of Psychiatry and Psychotherapy, Medical Faculty Heinrich-Heine University, Düsseldorf, Germany.
Luisa BelkeChildren's Hospital Amsterdam Street, Cologne, Germany.
Franziska JänickeClinic for Psychiatry Marienborn, Düren, Germany.
Christine GrafInstitute of Movement and Neuroscience, German Sport University Cologne, Cologne, Germany.
Eckhard SchönauChildren's Hospital, University Hospital of Cologne and UniReha®, University Hospital of Cologne, Cologne, Germany.
Stephan BenderDepartment of Child and Adolescent Psychiatry Psychosomatic and Psychotherapy, University Hospital of Cologne, Cologne, Germany.
Oliver FrickeDepartment of Child and Adolescent Psychiatry, Psychotherapy and Child Neurology, Gemeinschaftskrankenhaus Herdecke and Chairs of Child and Adolescent Psychiatry, Witten/Herdecke University, Witten, Germany.ORCID http://orcid.org/0000-0001-7592-8653
University Hospital Cologne · DEGerman Sport University Cologne · DEHeinrich Heine University Düsseldorf · DEKrankenhaus Düren · DEUniversity of Cologne · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent meta-analyses reveal a moderate effect of physical activity (PA) in the treatment of adolescent depression. However, not only the underlying neurobiological mechanisms, also the influences of placebo-related motivational factors (beliefs and expectancies in sporting, enjoyment and prior sports experiences), are still unclear. Based on the data of our prior study "Mood Vibes", we hypothesized that placebo-inherent factors like positive prior sports experiences and motivational factors, (positive beliefs, expectancies, and enjoyment related to PA), would increase the effects of an add-on exercise-therapy in juvenile depression. From 64 included depressed adolescents, 41 underwent an intensive add-on PA-therapy. Motivational factors were assessed using sport-specific scales. The changes in depression scores under treatment were rated by self-rating scale (German "Childhood Depression Inventory", (DIKJ)). A mixed model for repeated measures (MMRM) was used to analyze the effects of the different motivational variates on DIKJ. While prior sports experiences had no impact, motivational factors showed a significant effect on PA-induced changes in DIKJ scores (p = 0.002). The demotivated participants improved less, whereas it was sufficient to be neutral towards sporting to benefit significantly more. Motivational placebo-related factors (beliefs, expectancies and enjoyment regarding PA) affected the outcomes of an exercise treatment in depressed adolescents. Yet, a neutral mindset was sufficient to profit more from PA. Prior sporting in the sense of positive conditioning and as a protective factor did not play a role. Knowledge about these influences could in a second step help to develop tailored therapies.

Indexed as

ExerciseSportsAdolescentAffectChildExercise TherapyHumansMotivationAdolescent depressionEnjoymentExerciseMotivationPhysical activityPlacebo

Identifiers

PMID33709258
PMCPMC9343287
OpenAlexW3135691674

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.