Evidence map›Paper›PMID 33709212›Full record

ArticleAIDS and behavior2021

A Pilot Study to Evaluate the Impact of the HIV Infant Tracking System (HITSystem 2.0) on Priority Prevention of Mother-to-Child Transmission (PMTCT) Outcomes.

Sarah Finocchario-Kessler, Melinda Brown, May Maloba, Niaman Nazir, Catherine Wexler, Kathy Goggin, Jacinda K Dariotis, Natabhona Mabachi, Silas Lagat, Sharon Koech and 1 more

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Sarah Finocchario-KesslerDepartment of Family Medicine, University of Kansas Medical Center, Mailstop 4010, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA. skessler2@kumc.edu.ORCID http://orcid.org/0000-0002-7604-5606
Melinda BrownDepartment of Family Medicine, University of Kansas Medical Center, Mailstop 4010, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA.
May MalobaGlobal Health Innovations, Nairobi, Kenya.
Niaman NazirDepartment of Family Medicine, University of Kansas Medical Center, Mailstop 4010, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA.
Catherine WexlerDepartment of Family Medicine, University of Kansas Medical Center, Mailstop 4010, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA.
Kathy GogginHealth Services and Outcomes Research, Children's Mercy, Kansas City, MO, USA.
Jacinda K DariotisDepartment of Human Development and Family Studies & Family Resiliency Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Natabhona MabachiDepartment of Family Medicine, University of Kansas Medical Center, Mailstop 4010, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA.
Silas LagatMinistry of Health, Nandi County, Kenya.
Sharon KoechGlobal Health Innovations, Nairobi, Kenya.
Brad GautneyGlobal Health Innovations, Dallas, TX, USA.
University of Kansas Medical Center · USMinistry of Health · KEChildren's Mercy Hospital · USHealth Innovations (United States) · USUniversity of Illinois Urbana-Champaign · US

Funding

Piloting at-birth point of care HIV testing strategies in KenyaR01HD076673 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KESSLER, SARAH FINOCCHARIO · 2013 to 2017
$3.4M
Adapting the HITSystem to Support PMTCT Retention and ART AdherenceR34MH107337 · NIMH · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KESSLER, SARAH FINOCCHARIO · 2015 to 2017
$636k
Eunice Kennedy Shriver National Institute of Child Health and Human Development 076673NIMH NIH HHS R34 MH107337NIMH NIH HHS R34MH107337
6 · The paper itself

Abstract

We assessed the preliminary impact of the adapted HIV Infant Tracking System (HITSystem v2.0) intervention on prevention of mother-to-child transmission (PMTCT) outcomes using a matched cluster randomized design in two Kenyan government hospitals. Between November 2017 and June 2019, n = 157 pregnant women with HIV were enrolled and followed from their first PMTCT appointment until 12-weeks postpartum. Data from 135 women were analyzed (HITSystem 2.0: n = 53, standard of care (SOC): n = 82), excluding eight deaths, eight pregnancy losses, and six transfers/moves. The primary outcome, complete PMTCT retention, is an aggregate measure of attendance at all scheduled antenatal appointments, hospital-based delivery, and infant HIV-testing before 7-weeks postnatal. HITSystem 2.0 participants were more likely to receive complete PMTCT services compared to SOC (56.6% vs. 17.1% p < 0.001). In multivariate modeling, HITSystem 2.0 was the strongest predictor of complete PMTCT retention (aOR 5.7, [1.2-90.8], p = 0.032). SOC participants had 1.91 increased hazard rate of PMTCT disengagement; (aHR 6.8, [2.2-21.1]; p < 0.001).

Indexed as

HIV InfectionsPregnancy Complications, InfectiousChildFemaleHumansInfantInfectious Disease Transmission, VerticalKenyaPilot ProjectsPregnancyAppointment attendanceART adherenceComplete PMTCT retentionEHealthFacility deliveriesHIVKenyaMHealthPMTCTPregnancyRetentionWomen

Identifiers

PMID33709212
PMCPMC8224224
OpenAlexW3134719122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.