Evidence map›Paper›PMID 33709156›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Neuropsychological profiles in children and young adults with spina bifida.

C Rendeli, E Ausili, R Moroni, M Capriati, L Massimi, C Zanetti

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C RendeliDipartimento Scienze della salute della donna, del bambino e di sanità pubblica - Unità Operativa Spina Bifida e Uropatie Malformative, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. claudia.rendeli@policlinicogemelli.it.ORCID https://orcid.org/0000-0002-5948-1617
E AusiliDipartimento Scienze della salute della donna, del bambino e di sanità pubblica - Unità Operativa Spina Bifida e Uropatie Malformative, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
R MoroniDirezione Scientifica - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0002-3477-6136
M CapriatiDipartimento Scienze della salute della donna, del bambino e di sanità pubblica - Unità Operativa Spina Bifida e Uropatie Malformative, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
L MassimiScienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo, Rome, Italy.
C ZanettiDipartimento Scienze della salute della donna, del bambino e di sanità pubblica - Unità Operativa Spina Bifida e Uropatie Malformative, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Agostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA total of 43 Italian children, aged between 6 and 16 years, diagnosed with spina bifida, myelomeningocele, and shunted hydrocephalus have been described clinically and completed a neuropsychological battery in order to evaluate their cognitive, personality, and behavior profile.

methodsEnrolled children underwent cognitive assessment by means of the Weschler WISC-IV cognitive test and assessment of the attention sustained through the LEITER test. In addition, parents were asked, in order to obtain a personality and behavior profile of the children, to fill in a "CBCL 6-18 years" questionnaire and to fill in a Barthel Index questionnaire.

resultsProcessing Speed Index of the WISC-IV QI scale was statistically significant (p = 0.027), with the highest value presented by autonomous patients (95.8 ± 12.8) and the lowest by patients using a wheelchair (75.5 ± 19). WISC-IV QI mean value is 98 (±15.7) for lipoma patients and 78.7 (±17.6) for LMMC and MMC patients (p = 0.001). In more detail, Perceptual Reasoning (p < 0.0005), Working Memory (p = 0.01), and Processing Speed Index (p = 0.001) highlighted a significant difference between the groups. The attention sustained subscale of the LEITER presented a mean of 6.9 (±3.1) for lipoma patients and a men value of 4.6 (±3.1) for LMMC and MMC patients (p = 0.024). Patients with hydrocephalus had statistically significant worse cognition and autonomy (Barthel Index) score (p < 0.001) compared with those without hydrocephalus, and normal scores regarding attention and depression scales.

conclusionThese results can be useful in planning dedicated therapeutic protocols such as suitable rehabilitation treatments, speech therapy, psychomotor skills, and cognitive enhancement and to develop prevention protocols particularly tailored for children with hydrocephalus who appear to have the more deficient skills.

Indexed as

HydrocephalusMeningomyeloceleSpinal DysraphismAdolescentChildHumansMaleNeuropsychological TestsWechsler ScalesExecutive function assessmentGeneral Intelligence QIHydrocephalusMyelomeningoceleNeuropsychological profilesSpina bifida

Identifiers

PMID33709156
PMCPMC8184547
OpenAlexW3135881900

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.