Evidence map›Paper›PMID 33709134›Full record

Trial reportThe Journal of nutrition2021

Household Water and Food Insecurity Are Positively Associated with Poor Mental and Physical Health among Adults Living with HIV in Western Kenya.

Joshua D Miller, Edward A Frongillo, Elly Weke, Rachel Burger, Pauline Wekesa, Lila A Sheira, A Rain Mocello, Elizabeth A Bukusi, Phelgona Otieno, Craig R Cohen and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02815579 (Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02815579 nacompletednot on this map

Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2019Enrolled746ConditionsHIVArmsShamba Maisha Intervention
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Interacting Water Insecurity and Food Insecurity: Recent Advances in Theory and Application.American journal of human biology : the official journal of the Human Biology Council · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joshua D MillerDepartment of Anthropology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-2171-856X
Edward A FrongilloDepartment of Health Promotion, Education, and Behavior, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-8265-9815
Elly WekeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Rachel BurgerDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.
Pauline WekesaCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lila A SheiraDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
A Rain MocelloDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.
Elizabeth A BukusiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Phelgona OtienoCentre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Craig R CohenDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.
Sheri D WeiserDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-7807-4072
Sera L YoungDepartment of Anthropology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-1763-1218

Funding

Agricultural intervention for food security and HIV healthoutcomes in KenyaR01MH107330 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, WEISER, SHERI DAWN · 2015 to 2019
$4.7M
Sustainable Development for Improved HIV Health and Prevention in Kenya (SD4H-Kenya)D43TW011306 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUKUSI, ELIZABETH ANNE, COHEN, CRAIG R · 2020 to 2024
$1.9M
FIC NIH HHS D43 TW011306NIMH NIH HHS R01 MH107330
6 · The paper itself

Abstract

backgroundHousehold food insecurity (FI) and water insecurity (WI) are prevalent public health issues that can co-occur. Few studies have concurrently assessed their associations with health outcomes, particularly among people living with HIV.

objectivesWe aimed to investigate the associations between FI and WI and how they relate to physical and mental health.

methodsFood-insecure adult smallholder farmers living with HIV in western Kenya were recruited to participate in a cluster-randomized controlled trial of a multisectoral agricultural and asset loan intervention. We used baseline data on experiences of FI (using the Household Food Insecurity Access Scale, range: 0-27) and WI (using a modified scale developed for this region, range: 0-51) in the prior month (n = 716). Outcomes included probable depression (using the Hopkins Symptom Checklist), fatigue and diarrhea in the prior month, and overall mental and physical health (using the Medical Outcomes Study HIV Health Survey, range: 0-100). We first assessed Pearson correlations between FI, WI, and sociodemographic characteristics. We then developed 3 regressions for each health outcome (control variables and FI; control variables and WI; control variables, FI, and WI) and compared model fit indexes.

resultsCorrelations between household FI, WI, and wealth were low, meaning they measure distinct constructs. FI and WI were associated with numerous physical and mental health outcomes; accounting for both resource insecurities typically provided the best model fit. For instance, when controlling for FI, each 10-point higher WI score was associated with a 6.42-point lower physical health score (P < 0.001) and 2.92 times greater odds of probable depression (P < 0.001).

conclusionsAssessing both FI and WI is important for correctly estimating their relation with health outcomes. Interventions that address food- and water-related issues among persons living with HIV concurrently will likely be more effective at improving health than those addressing a single resource insecurity. This trial was registered at clinicaltrials.gov as NCT02815579.

Indexed as

Drinking WaterFood InsecurityHealth StatusHIV InfectionsMental HealthAdultFood SupplyHumansKenyaDrinking Waterdiarrheafatiguemental and physical healthprobable depressionresource insecurity

Identifiers

PMID33709134
PMCPMC8243794

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.