Evidence map›Paper›PMID 33709098›Full record

SynthesisEuropean heart journal2021

The association between coronary graft patency and clinical status in patients with coronary artery disease.

Mario Gaudino, Antonino Di Franco, Deepak L Bhatt, John H Alexander, Antonio Abbate, Lorenzo Azzalini, Sigrid Sandner, Garima Sharma, Sunil V Rao, Filippo Crea and 2 more

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05129228 (Intraoperative Optical Coherence Tomography of the Saphenous Vein Conduit in Patients Undergoing Coronary Artery Bypass Surgery), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05129228 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Intraoperative Optical Coherence Tomography of the Saphenous Vein Conduit in Patients Undergoing Coronary Artery Bypass Surgery

TypeinterventionalSponsorSt. Francis Hospital, New YorkRan2022 to 2026Enrolled760ConditionsCoronary Bypass Graft StenosisArmsOCT-guided saphenous vein CABG
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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  13. One-month DAPT with ticagrelor and aspirin for patients undergoing coronary artery bypass grafting: rationale and design of the randomised, multicentre, double-blind, placebo-controlled ODIN trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 4 countries.

Mario GaudinoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA.
Antonino Di FrancoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA.
Deepak L BhattHeart and Vascular Center, Brigham and Women's Hospital, Harvard Medical School, 70 Francis St, Boston, MA 02115, USA.
John H AlexanderDuke Clinical Research Institute, Duke University Medical Center, 2400 Pratt St, Durham, NC 27705, USA.
Antonio AbbateDivision of Cardiology, VCU Pauley Heart Center and Wright Center for Clinical and Translational Research, Virginia Commonwealth University, 1200 E Marshall St, Richmond, VA 23219, USA.
Lorenzo AzzaliniDivision of Cardiology, VCU Health Pauley Heart Center, Virginia Commonwealth University, 1200 E Marshall St, Richmond, VA 23219, USA.
Sigrid SandnerDepartment of Cardiac Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.
Garima SharmaDivision of Cardiology, Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Diseases, Johns Hopkins University School of Medicine, 1800 Orleans St, Baltimore, MD 21287, USA.
Sunil V RaoDuke Clinical Research Institute, Duke University Medical Center, 2400 Pratt St, Durham, NC 27705, USA.
Filippo CreaDepartment of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 1, Roma 00168, Italy.
Stephen E FremesDivision of Cardiac Surgery, Department of Surgery, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada.
Sripal BangaloreDivision of Cardiology, NYU Langone Health, 27 W 86th St, New York, NY 10024, USA.
Clinical Research Institute · USCornell University · USVirginia Commonwealth University · USBrigham and Women's Hospital · USJohns Hopkins University · USMedical University of Vienna · ATNYU Langone Health · USSunnybrook Health Science Centre · CAUniversità Cattolica del Sacro Cuore · IT

Funding

Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)R01HL152021 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAUDINO, MARIO FL, MASTERSON CREBER, RUTH MARIE · 2020 to 2024
$4.1M
NHLBI NIH HHS R01 HL152021
6 · The paper itself

Abstract

The concept of a direct association between coronary graft patency and clinical status is generally accepted. However, the relationship is more complex and variable than usually thought. Key issues are the lack of a common definition of graft occlusion and of a standardized imaging protocol for patients undergoing coronary bypass surgery. Factors like the type of graft, the timing of the occlusion, and the amount of myocardium at risk, as well as baseline patients' characteristics, modulate the patency-to-clinical status association. Available evidence suggests that graft occlusion is more often associated with non-fatal events rather than death. Also, graft failure due to competitive flow is generally a benign event, while graft occlusion in a graft-dependent circulation is associated with clinical symptoms. In this systematic review, we summarize the evidence on the association between graft status and clinical outcomes.

Indexed as

Coronary Artery DiseaseCoronary AngiographyCoronary Artery BypassCoronary VesselsGraft Occlusion, VascularHumansTreatment OutcomeVascular PatencyCABGGraft failurePatency

Identifiers

PMID33709098
PMCPMC8861263
OpenAlexW3134264910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.