ArticleCurrent opinion in behavioral sciences2021
Combined lesion-deficit and fMRI approaches in single-case studies: Unique contributions to cognitive neuroscience.
Article in Current opinion in behavioral sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identifying a brain network for musical rhythm: A functional neuroimaging meta-analysis and systematic review.Neuroscience and biobehavioral reviews · 2022Pooled it
- Cross-modal plasticity in a blind jazz pianist and prodigy.Neuroimage. Reports · 2026Article
- Dense Phenotyping of Human Brain Network Organization Using Precision fMRI.Annual review of psychology · 2026Review
- The New Zealand Genetic Frontotemporal Dementia Study (FTDGeNZ): a longitudinal study of pre-symptomatic biomarkers.Journal of the Royal Society of New Zealand · 2023Article
- Behavioral and neural underpinnings of empathic characteristics in a Humanitude-care expert.Frontiers in medicine · 2023Article
- Dissociable language and executive control deficits and recovery in post-stroke aphasia: An exploratory observational and case series study.Neuropsychologia · 2022Observational
- Largely intact memory for spatial locations during navigation in an individual with dense amnesia.Neuropsychologia · 2022Article
- A precise language network revealed by the independent component-based lesion mapping in post-stroke aphasia.Frontiers in neurology · 2022Article
- Comparing stimulus-evoked and spontaneous response of the face-selective multi-units in the human posterior fusiform gyrus.Neuroscience of consciousness · 2021Article
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Authors and funding
2 authors.
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Abstract
Although lesion-deficit case studies are foundational in cognitive neuroscience, published papers presenting single lesion cases are declining. In this review, we argue that there is a valuable place for single-case lesion-deficit research, especially when combined with functional neuroimaging methods, such as functional magnetic resonance imaging (fMRI). To support this, we present a summary of notable findings from single-case combined lesion-deficit and fMRI studies published in recent years (2017-2020). These studies show the unique value that this combined approach brings to the understanding of complex functions, brain-level connectivity, and plasticity and recovery. We encourage researchers to consider combining lesion-deficit and functional imaging methods in the analysis of single cases, as this approach affords unique opportunities to address challenging unanswered questions about brain-behavior relationships.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.